(1S,2S,3R,4S,5S)-5-((1,3-Dihydroxypropan-2-yl)amino)-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetraol (1S,2S,3R,4S,5S)-5-(1,3-二羟基丙烷-2-基氨基)-1-(羟甲基)-1,2,3,4-环己四醇

CAS 83480-29-9 MFCD00865496

化学结构图

83480-29-9
SMILES: OC[C@@]1(O)C[C@H](NC(CO)CO)[C@H](O)[C@@H](O)[C@@H]1O

化学属性

Mol. FormulaC10H21NO7
Mol. Weight267.28
Melting Point163.0 to 168.0 deg-C

别名和识别编码

Chemical Name(1S,2S,3R,4S,5S)-5-((1,3-Dihydroxypropan-2-yl)amino)-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetraol
Synonym 3,4-Dideoxy-4-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-D-epi-inositol 3,4-Dideoxy-4-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-D-epi-inositol N-(1,3-Dihydroxyprop-2-yl)valiolamine N-(1,3-Dihydroxyprop-2-yl)valiolamine
MDL NumberMFCD00865496
Chemical Name Translation(1S,2S,3R,4S,5S)-5-(1,3-二羟基丙烷-2-基氨基)-1-(羟甲基)-1,2,3,4-环己四醇
CAS Number83480-29-9
Reaxys-RN5430708
PubChem Substance ID160871113
Merck Number10029
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分类

  • {SNA} Carbohydrates A to Z, Carbohydrates P-Z, Disaccharide, 生化试剂, 碳水化合物

相关文献及参考

  • [2]. Ikenoue, T., et al., Effect of a new hypoglycemic agent, A-4166 [(-)-N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine], on postprandial blood glucose excursion: comparison with voglibose and glibenclamide. Biol Pharm Bull, 1997. 20(4): p. 354-9.
  • [3]. Moritoh, Y., K. Takeuchi, and M. Hazama, Combination treatment with alogliptin and voglibose increases active GLP-1 circulation, prevents the development of diabetes and preserves pancreatic beta-cells in prediabetic db/db mice. Diabetes Obes Metab, 2010. 12(3): p. 224-33.
  • [1]. Chen, X., Y. Zheng, and Y. Shen, Voglibose (Basen, AO-128), one of the most important alpha-glucosidase inhibitors. Curr Med Chem, 2006. 13(1): p. 109-16.
  • [1]. Chen, X., Y. Zheng, and Y. Shen, Voglibose (Basen, AO-128), one of the most important alpha-glucosidase inhibitors. Curr Med Chem, 2006. 13(1): p. 109-16.
  • [2]. Ikenoue, T., et al., Effect of a new hypoglycemic agent, A-4166 [(-)-N-(trans-4-isopropylcyclo

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECSNM7524600
Storage condition <0°C

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Glucosidase  (葡萄糖苷酶)

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