Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-,hydrochloride (1:1) [6-羟基-2-(4-羟苯基)苯并[b]噻酚-3-基]-[4-[2-(1-哌啶基)乙氧基]-苯基]-甲酮盐酸盐

CAS 82640-04-8 MFCD01938233

化学结构图

82640-04-8
SMILES: Cl.O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12

化学属性

Mol. FormulaC28H27NO4S · HCl
Mol. Weight510.04

别名和识别编码

Chemical NameMethanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-,hydrochloride (1:1)
Synonym Evista Keoxifene Keoxifene Hydrochloride Keoxifene hydrochloride LY 156758 [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone hydrochloride LY 139481 LY 156758 LY-139481 LY-156758 LY139481 LY156758 Raloxifene Raloxifene HCl Raloxifene Hydrochloride Raloxifene hydrochloride
MDL NumberMFCD01938233
PubChem Substance ID54900
CAS Number82640-04-8
LabNetwork Molecule IDLN00192660
InChIInChI=1S/C28H27NO4S.ClH/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29;/h4-13,18,30-31H,1-3,14-17H2;1H
Chemical Name Translation[6-羟基-2-(4-羟苯基)苯并[b]噻酚-3-基]-[4-[2-(1-哌啶基)乙氧基]-苯基]-甲酮盐酸盐
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SA} Antitumor Agents, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cancer Research, Cell Biology, Cell Signaling and Neuroscience, Chemopreventive Agents,
  • Antitumor Agents, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cancer Research, Cell Biology, Cell Signaling and Neuroscience, Chemopreventive Agents, Cytokines, Growth Factors and Hormones, Eli Lilly, Estrogen, Estrogen Modulators, Estrogen Response Modifiers, Gene Regulation, Hormones, R, Steroid Hormones, Tumor Growth Regulation
  • {SNA} Approved Therapeutics/Drug Candidates,

相关文献及参考

  • Fitzpatrick, S.L., Effect of estrogen agonists and antagonists on induction of progesterone receptor in a rat hypothalamic cell line. Endocrinology 140 , 3928, (1999) 摘要
  • Barreto, G., et al., Selective Estrogen Receptor Modulators Decrease Reactive Astrogliosis in the Injured Brain: Effects of Aging and Prolonged Depletion of Ovarian Hormones Endocrinology 150 , 5010-5, (2009) 摘要
  • Merck 14 ,8098

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Hazard statements
  • H351 Suspected of causing cancer 怀疑致癌
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P308+P313
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Hormones - Cytokines, Growth Factors and Hormones
  6. Steroid Hormones - Hormones
  7. Estrogen - Steroid Hormones

相关产品推荐