(S)-Glycyl-H-1152 (hydrochloride)

CAS 913844-45-8 MFCD09971082

化学结构图

913844-45-8
SMILES: Cl.Cl.CC1=CN=CC2C=CC=C(C1=2)S(=O)(=O)N1CCCN(C[C@@H]1C)C(=O)CN

化学属性

Mol. FormulaC18H26Cl2N4O3S
Mol. Weight449.395

别名和识别编码

Chemical Name(S)-Glycyl-H-1152 (hydrochloride)
CAS Number913844-45-8
Synonym 2-Amino-1-[(3S)-hexahydro-3-methyl-4-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepin-1-yl]ethanone Hydrochloride (2S)-4-(Aminoacetyl)hexahydro
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分类

  • Inhibitors
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Protein Kinase Inhibitors and Activators,

产品应用

  • A glycyl analog of Rho-kinase (ROCK) inhibitor that inhibits ROCK with an improved selectitity; for treatment of hypertension and arteriosclerosis.

相关文献及参考

  • Tamura, M., et al.: Biochim. Biophys. Acta, 1754, 245 (2005),

系列性分类

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