ANTI-SVG-30 TRIFLUOROACETATE SALT
CAS N/A MFCD04974485
化学结构图
SMILES: C[C@@H](O)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](N)CC1C=CC=CC=1)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(N)=O.OC(=O)C(F)(F)F
化学属性
| Mol. Formula | C161H274N48O46S |
|---|---|
| Mol. Weight | 3650.26 |
别名和识别编码
| Chemical Name | Antisauvagine-30 trifluoroacetate salt |
|---|---|
| Synonym | [D-Phe11,His12]-Sauvagine fragment 11-40 trifluoroacetate salt Anti-SVG-30 [D-Phe11,His12]-Sauvagine fragment 11-40 trifluoroacetate salt Anti-SVG-30 |
| MDL Number | MFCD04974485 |
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分类
- {SNA} AN-AZ, Bioactive Small Molecules, CRF, Cell Biology, Cell Signaling and Neuroscience, Neuropeptides, Peptides and Proteins, Peptides for Cell Biology, Releasing Factors
- {SNA} CRF, Neuropeptides, Peptides and Proteins, Peptides for Cell Biology, Releasing Factors, 细胞信号转导和神经科学, 细胞生物学
- AN-AZ, Bioactive Small Molecules, CRF, Cell Biology, Cell Signaling and Neuroscience, Neuropeptides, Peptides and Proteins, Peptides for Cell Biology, Releasing Factors
相关文献及参考
- Brauns, O., et al., Secondary structure of antisauvagine analogues is important for CRF receptor antagonism: development of antagonists with increased potency and receptor selectivity. Peptides 23 , 1817-27, (2002)
- Wang, L., et al., Peripheral urocortin inhibits gastric emptying and food intake in mice: differential role of CRF receptor 2. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281 , 1401-10, (2001)
- Takahashi, L.K., et al., Antagonism of CRF(2) receptors produces anxiolytic behavior in animal models of anxiety. Brain Res. 902 , 135-42, (2001) 摘要
- Higelin, J., et al., 125I-Antisauvagine-30: a novel and specific high-affinity radioligand for the characterization of corticotropin-releasing factor type 2 receptors. Neuropharmacology 40 , 114-22, (2001)
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