2-Bromothiazole 2-溴噻唑

CAS 3034-53-5 MFCD00005316

化学结构图

3034-53-5
SMILES: Brc1nccs1

化学属性

Mol. FormulaC3H2BrNS
Mol. Weight164.02
Boiling Point171°C at 760 mmHg
Density1.82
Refractive index1.5910 to 1.5950
Flash Point67°C
TSCAYes
Solubility不溶
pH:A
Melting Point39.5 °C

别名和识别编码

Chemical Name2-Bromothiazole
CAS Number3034-53-5
Alfabeta NameBROMOTHIAZOLE 2-
MDL NumberMFCD00005316
Synonym 2-Bromothiazole {LY} 2-Bromothiazole {} {LY} 2-Bromothiazole {} {} {LY} 2-Bromothiazole {} {} {} {LY} 2-Bromothiazole {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {} {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Bromothiazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
EC Number221-229-4
Beilstein Registry Number105724
PubChem Substance ID76430
Chemical Name Translation2-溴噻唑
Reaxys-RN105724
InChIKeyRXNZFHIEDZEUQM-UHFFFAOYSA-N
LabNetwork Molecule IDLN00004618
InChIInChI=1S/C3H2BrNS/c4-3-5-1-2-6-3/h1-2H
Canonical SMILESBrC1=NC=CS1
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分类

  • Sulfur & Selenium Compounds
  • Mutagenesis Research Chemicals
  • Heterocycles
  • {SNA} Building Blocks, C3 to C7, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Thiazoles

产品应用

  • 用于 5- 和 7-氮杂吲哚 N-芳基化反应的芳基卤化物。参与铜催化的氰化反应生成 2-氰基噻唑.

相关文献及参考

  • 2-Lithiothiazole can be obtained by direct lithiation of thiazole or, more conveniently, by exchange with 2-bromothiazole using n-BuLi: J. Org. Chem., 53, 1748 (1988). It behaves as a valuable formyl anion equivalent, and as such has been applied, mainly by Dondoni's group, in the syntheses of a variety of products; see, e.g.: Tetrahedron Lett., 34, 7319, 7323, 7327 (1993). See also 2-(Trimethyl­silyl)­thiazole, B21903. Reaction of 2-lithiothiazole with nitrones gives ɑ-aminoaldehydes: Tetrahedron Lett., 33, 4221 (1992); stereocontrolled addition to C-galacto-pyranosylnitrone has been used in syntheses of destomic acid, a component of the antibiotics destomycin and hygromycin, and of lincosamine, the sugar component of the anticancer antibiotic lincomycin: Synlett, 78 (1993). For applications of 2-lithiothiazole in the synthesis of the aza-sugar (+)-galactostsin, see: J. Org. Chem., 60, 4749 (1995). The Thiazole Aldehyde Synthesis has been reviewed by Dondoni: Synthesis, 1681 (1998).
  • Voogd, C.E., et al.: Mutation Research, Genetic Toxicology Testing, 118, 153 (1983),

安全信息

Warnings IRRITANT, FLAMMABLE
Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P403+P235
Personal Protective Equipment Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US) Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US)
Storage condition -20°C {LY} -20°C 2-8°C <0°C <;0 {} {LY} -20°C {} {} {LY} -20°C {} {} {} {LY} -20°C {} {} {} {} {LY} -20°C {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard statements
  • H227 Combustible liquid 可燃液体
Hazard Codes Xi,F
UN Number 1993

其他信息

  • Sigma Aldrich:3034-53-5(sigmaaldrich)
  • 图谱信息:2-溴噻唑(3034-53-5)核磁图( 1 HNMR) 2-溴噻唑(3034-53-5)红外图谱(IR1) 2-溴噻唑(3034-53-5)核磁图( 13 CNMR) 2-溴噻唑(3034-53-5)质谱(MS)
  • MOL 文件:3034-53-5.mol
  • 下游产品:2-溴-5-甲醛基噻唑 --> 噻唑-5-甲酸 --> 1,3-噻唑-2-甲酰氯 --> 5-溴噻唑 --> 噻唑-2-甲酸
  • 海关编码:29341000
  • 用途一:用作制2-乙酰基噻唑的中间体
  • Acros Organics:2-溴噻唑 2-Bromothiazole, 98+%(3034-53-5)
  • TCI Shanghai:2-溴噻唑 2-Bromothiazole,>;97.0%(GC)(3034-53-5)
  • 上游原料:硝酸 --> 磷酸
  • 检测方法:GC,NMR
  • Alfa Aesar:2-溴噻唑,99% 2-Bromothiazole, 99%(3034-53-5)
  • MSDS 信息:2-Bromo-1,3-thiazole(3034-53-5).msds
  • 2-溴噻唑价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 B1280 2-溴噻唑 2-Bromothiazole 250G 7780元 2014/06/02 B1280 2-溴噻唑 2-Bromothiazole 25G 1370元 2010/06/21 CC09510DA 2-溴噻唑 2-bromo-1,3-thiazole 1 GR 315元

系列性分类


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