2-Phenylindole 2-苯基吲哚

CAS 948-65-2 MFCD00005608

化学结构图

948-65-2
SMILES: c1ccc(-c2cc3ccccc3[nH]2)cc1

化学属性

Mol. FormulaC14H11N
Mol. Weight193.25
Density1.156
Melting Point188-190°C
TSCAYes
Boiling Point250 °C at 10 mmHg
Flash Point250°C/10mm
Appearance 黄色或酱红色叶状结晶。 溶于乙醚、苯、乙酸、氯仿和热二硫化碳，微溶于热水，不溶于稀无机酸。

别名和识别编码

Chemical Name2-Phenylindole
Synonym 2-Phenyl-1H-indole {LY} 2-Phenyl-1H-indole {} {LY} 2-Phenyl-1H-indole {} {} {LY} 2-Phenyl-1H-indole {} {} {} { {} {} {} {LY} 2-Phenyl-1H-indole {} {} {} {} {LY} 2-Phenyl-1H-indole {} {} {} {} {} {LY} 2-Phenyl-1H-indole {} {} {} {} {} {} {LY} 2-Phenyl-1H-indole {} {} {} {} {} {} {} {LY} 2-Phenyl-1H-indole {} {} {} {} {} {} {} {} {LY} 2-Phenyl-1H-indole {} {} {} {} {} {} {} {} {} {LY} 2-Phenyl-1H-indole {} {} {} {} {} {} {} {} {} {} {LY} 2-Phenyl-1H-indole {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Phenyl-1H-indole {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Phenyl-1H-indole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Phenyl-1H-indole {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Phenyl-1H-indole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Phenyl-1H-indole {} {} {} {} {} {} {} {} {} {} {
MDL NumberMFCD00005608
CAS Number948-65-2
EC Number213-436-3
Beilstein Registry Number132356
PubChem Substance ID13698
Reaxys-RN132356
Chemical Name Translation2-苯基吲哚
LabNetwork Molecule IDLN00222486
InChIInChI=1S/C14H11N/c1-2-6-11(7-3-1)14-10-12-8-4-5-9-13(12)15-14/h1-10,15H
Canonical SMILESN1C(=CC2=C1C=CC=C2)C1=CC=CC=C1
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Building Blocks, C13 to C27, Chemical Synthesis, Heterocyclic Building Blocks, Indoles
  • {uni_hamburg} no charge; nitrogen heterocycle; carbocycle; aromatic; large ring; fused rings; 5ring; 6ring; 9ring; 1fragment

相关文献及参考

  • Short: II/3
  • Short: EINECS
  • Beilstein:20,467

安全信息

Signal word Danger
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
  • S39 Wear eye/face protection 戴眼睛/面孔保护装置；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
Risk Statements
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSNM1272500
Hazard Codes Xi
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >6 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 10,44,1960

Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • 上游原料:乙醇 --> 乙酸 --> 丙酮 --> 多聚磷酸 --> 乙酰苯 --> 苯肼 --> 联苯 --> 苯甲酰胺 --> 2-溴苯乙酮
  • Alfa Aesar:2-苯基吲哚,95% 2-Phenylindole, 95%(948-65-2)
  • Acros Organics:2-Phenylindole, 99%(948-65-2)
  • 2-苯基吲哚价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 P0188 2-苯基吲哚 2-Phenylindole 250G 1320元 2014/06/02 P0188 2-苯基吲哚 2-Phenylindole 25G 228元 2010/06/21 130685000 2-苯基吲哚 2-Phenylindole 99% 500 GR 4401元
  • MOL 文件:948-65-2.mol
  • 图谱信息:2-苯基吲哚(948-65-2)核磁图( 1 HNMR) 2-苯基吲哚(948-65-2)红外图谱(IR2) 2-苯基吲哚(948-65-2)红外图谱(IR1) 2-苯基吲哚(948-65-2)核磁图( 13 CNMR) 2-苯基吲哚(948-65-2)质谱(MS)
  • 检测方法:HPLC
  • 用途二:该品主要作为阳离子染料中间体，用于生产阳离子橙2GL、阳离子红BL、阳离子红2GL，用于染料生产时往往先经甲基化，进一步制成N-甲基-2-苯基吲哚。甲基化剂为硫酸二甲酯，反应在氯苯溶剂中进行，在60-65℃反应，收率为83.5%。2-苯基吲哚也用作乳液法聚氯乙烯的热稳定剂。
  • MSDS 信息:2-Phenylindole(948-65-2).msds
  • Sigma Aldrich:948-65-2(sigmaaldrich)
  • 下游产品:阳离子黄 X-3RL
  • TCI Shanghai:2-苯基-1H-吲哚 2-Phenylindole,>;98.0%(GC)(948-65-2)
  • 用途一:用作PVC玻璃纸稳定剂及染料中间体
  • 方法一:由苯肼与苯乙酮缩合后，再在氯化锌存在下闭环而制得2-苯基吲哚。除上述的Fisher法外，可将溴代苯乙酮与过量的苯胺加热反应，或将N-（2-甲基苯基）苯甲酰胺和乙醇钠隔绝空气于360-380℃加热，都可制得2-苯基吲哚。原料消耗定额：苯乙酮（98%）735kg/t、苯肼（游离100%）675kg/t、二甲苯900kg/t、冰醋酸15kg/t、氯化锌1230kg/t、盐酸（30%）810kg/t。

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Indazoles 吲唑
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Indoles 吲哚
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Indolines 吲哚啉
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Indoles 吲哚
  5. C13 to C27 - Indoles
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Chemicals by Class 化学分类法
  4. Indoles