Pyridine N-Oxide 吡啶-N-氧化物

CAS 694-59-7 MFCD00006194

化学结构图

694-59-7
SMILES: [O-][n+]1ccccc1

化学属性

Mol. FormulaC5H5NO
Mol. Weight95.10 g/mol
Density1.422
Flash Point143°(289°F)
TSCAYes
Boiling Point270
Melting Point62-68
Solubility可溶
Stability易吸潮
Appearance 无色晶体

别名和识别编码

Chemical NamePyridine N-oxide, 98%
Synonym 1-Oxidopyridin-1-ium 1-Oxylatopyridinium 1-oxidePyridine 3-PICOLIN-N-OXIDE N-氧化吡啶 N-氧化吡啶;N-氧代吡啶 N-氧化嘧啶 PYRIDINE-1-OXIDE PYRIDINE-1-OXIDE 97% PYRIDINE-N-OXIDE Pyridin-1-oxid Pyridin-N-oxid Pyridine 1-oxide Pyridine N-Oxide pyridine N-oxide pyridine N-oxide perchlorate {} {} {} {} {} {PubChem} pyridine N-oxide perchlorate {} {} {} {} {} {} {PubChem} pyridine N-oxide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} pyridine N-oxide perchlorate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} pyridine N-oxide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
CAS Number694-59-7
EC Number211-774-6
Beilstein Registry Number105257
MDL NumberMFCD00006194
Merck Number7972
PubChem Substance ID12753
Reaxys-RN105257
Chemical Name Translation吡啶-N-氧化物
Wiswesser Line NotationT6NJ AO
LabNetwork Molecule IDLN00111917
InChIInChI=1S/C5H5NO/c7-6-4-2-1-3-5-6/h1-5H
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分类

  • {SNA} Building Blocks, C5, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines
  • {uni_hamburg} no charge; nitrogen heterocycle; 6RingOnly; 6ring; 1fragment

相关文献及参考

  • Short: II/19c
  • Short: II/19b
  • Short: II/14a
  • Mild oxidant for conversion of unactivated alkyl halides to aldehydes or ketones: J. Org. Chem., 22, 1135 (1957); 35, 244 (1970); Tetrahedron, 33, 1845 (1977). Substituted acetic acids and their anhydrides: J. Org. Chem., 38, 3737 (1973), as well as ɑ-bromo and ɑ-chloro acids: J. Org. Chem., 31, 3058 (1966); J. Am. Chem. Soc., 89, 4968 (1967), can undergo oxidative decarboxylation to aldehydes and ketones.

安全信息

Signal word
GHS Symbol
WGK Germany3
Safety Statements
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P301+P317
  • P302+P350
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSUT6410000
Storage condition 2-8°C Hygroscopic
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xi Xi,Xn
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 48,371,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 12,355,1983

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#04070

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1425 mg/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volu

其他信息

  • F:21
  • Sigma Aldrich:694-59-7(sigmaaldrich)
  • 下游产品:4-氨基吡啶 --> 4-氯-2-氰基吡啶 --> 4-苄氧基-2(1H)-吡啶酮
  • 存储注意事项:湿度敏感
  • TCI Shanghai:吡啶-N-氧化物 Pyridine N-Oxide,>;95.0%(T)(694-59-7)
  • Alfa Aesar:N-氧化吡啶,95% Pyridine N-oxide, 95%(694-59-7)
  • 吡啶-N-氧化物价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 P0557 吡啶N-氧化物 Pyridine N-Oxide 25G 267元 2014/06/02 P0557 吡啶N-氧化物 Pyridine N-Oxide 500G 1920元 2010/06/21 157691000 吡啶-N-氧化物 Pyridine-N-oxide 98% 100 GR 636元
  • MSDS 信息:Pyridine-N-oxide(694-59-7).msds
  • 敏感性:Hygroscopic
  • 海关编码:29333999
  • 图谱信息:吡啶-N-氧化物(694-59-7)质谱(MS) 吡啶-N-氧化物(694-59-7)核磁图( 13 CNMR) 吡啶-N-氧化物(694-59-7)红外图谱(IR2) 吡啶-N-氧化物(694-59-7)核磁图( 1 HNMR) 吡啶-N-氧化物(694-59-7)红外图谱(IR3) 吡啶-N-氧化物(694-59-7)红外图谱(IR1)
  • Acros Organics:N-氧化吡啶 Pyridine-N-oxide, 98%(694-59-7)
  • MOL 文件:694-59-7.mol

系列性分类


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