2,4-Dichloroaniline 2,4-二氯苯胺

CAS 554-00-7 MFCD00007661

化学结构图

554-00-7
SMILES: Nc1ccc(Cl)cc1Cl

化学属性

Mol. FormulaC6H5Cl2N
Mol. Weight162
Boiling Point245 °C(lit.)
Melting Point59-62 °C(lit.)
Density1.567
Flash Point149°(300°F)
TSCAYes
Solubility微溶于水,溶于乙醇、乙醚。
Stability对光敏感

别名和识别编码

Chemical Name2,4-Dichloroaniline
CAS Number554-00-7
PubChem Substance ID11123
EC Number209-057-8
Beilstein Registry Number386422
MDL NumberMFCD00007661
Reaxys-RN386422
Synonym 2,4-DICHLOROANILINE PESTANAL 2,4-dca o,p-Dichloroaniline 2,4-二氯苯胺/间氯苯胺 2,4-二氯苯胺,99% 2,4-Dichloranilin Benzenamine, 2,4-dichloro- Benzenamine,2,4-dichloro- 2,4-dichlorobenzenamine 2,4-Dichloroanihne 2,4-dichloro 2,4-Dichlorobenzenamine 2,4-dichloro-aniline AKOS BBS-00003655 AURORA KA-688 2,4-DICHLORO-6-IODOANILINE 2,4-DICHLOROANILINE Aniline, 2,4-dichloro- 2,4-Dichlorophenylamine 1-AMINO-2,4-DICHLORO-BENZENE 2,4-二氯苯胺 LABOTEST-BB LTBB000651 2,4-Dichloroaniline 2,4-二氯苯胺 2,4-Dichloraminobenzol o,p-Dichloroaniline 2,4-dichloro-benzenamin o,p-Dichloranilin 2,4-Dichloroaniline,Pract. 2,4-dichloro-anilin TIMTEC-BB SBB007569
Chemical Name Translation2,4-二氯苯胺
Wiswesser Line NotationZR BG DG
LabNetwork Molecule IDLN00225008
InChIInChI=1S/C6H5Cl2N/c7-4-1-2-6(9)5(8)3-4/h1-3H,9H2
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分类

  • Alpha sort, Alphabetic, Amines, Analytical Standards, Analytical/Chromatography, Aromatics, Chemical Class, Chromatography, D, DIA - DIC, Environmental Standards, Pesticides & Metabolites
  • {S
  • {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment
  • {SNA} Alphabetical Index of Analytical Standards,
  • {SNA} Amines, Building Blocks, C6, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks
  • {SNA} Alphabetical Index of Analytical Standards, Amines, Analytical Standards, Analytical/Chromatography, Aromatics, Chemical Class, Chromatography,

产品应用

  • 有机合成中间体,农药中间体。

相关文献及参考

  • Short: III/31a
  • Short: III/20b
  • Beilstein:12,621

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H331 Toxic if inhaled 吸入中毒
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H301 Toxic if swallowed 吞食有毒
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • H302 Harmful if swallowed 吞食有害
  • H301+H311+H331
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes T,N T,N,Xi T;N
RTECSBX2600000
Precautionary statements
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P301+P310
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P305+P351+P338
  • P304+P340+P310
  • P301+P312+P330
  • P302+P350
  • P337+P313
  • P403+P233
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P332+P313
  • P302+P352+P310+P361+P364
  • P308+P311
  • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
  • P305+P351+P338+P337+P313
  • P405 Store locked up. 上锁保管。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
Signal word Danger Warning
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R33 Danger of cumulative effects 有累积作用的危险
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R50/53
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
UN Number UN3442 3442 UN 3442 6.1/PG 2 UN2811
Packing GroupII
Storage condition Light Sensitive 密封避光保存。 0-6°C
Hazard Class6.1
Warnings 危化品目录(2015)
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - cyanosis
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206512

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - cyanosis
   Lungs, Thorax, or Respiration - respiratory depre

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - cyanosis
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206512

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 113 mg/kg
TOXIC EFFECTS :
   Behavioral - hallucinations, distorted perceptions
   Lungs, Thorax, or Respiration - cyanosis
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie.  (Leipzig,
   Ger. Dem. Rep.)  V.1-109, 1873-1925.  For publisher information, see NSAPCC.
    Volume(issue)/page/year: 72,241

Restrict 危险品

其他信息

  • Hazard Note:Toxic/Irritant
  • F:8-9-23
  • 储运特性:库房通风低温干燥; 与氧化剂、食品添加剂、酸类分开存放
  • MSDS 信息:2,4-二氯苯胺(554-00-7).msds
  • 用途二:用作染料中间体。
  • 图谱信息:2,4-二氯苯胺(554-00-7)核磁图( 13 CNMR) 2,4-二氯苯胺(554-00-7)红外图谱(IR2) 2,4-二氯苯胺(554-00-7)红外图谱(IR1) 2,4-二氯苯胺(554-00-7)质谱(MS)
  • 类别:有毒物品
  • TCI Shanghai:2,4-二氯苯胺 2,4-Dichloroaniline,>;99.0%(GC)(554-00-7)
  • 用途一:用作抗感染药环丙沙星、农药杀菌剂酰胺唑、除草剂(PUMA)和染料的合成原料
  • Alfa Aesar:2,4-二氯苯胺,99% 2,4-Dichloroaniline, 99%(554-00-7)
  • 用途三:有机合成中间体,农药中间体。
  • Acros Organics:2,4-二氯苯胺 2,4-Dichloroaniline, 98%(554-00-7)
  • 2,4-二氯苯胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D0321 2,4-二氯苯胺 2,4-Dichloroaniline 25G 152元 2014/06/02 D0321 2,4-二氯苯胺 2,4-Dichloroaniline 500G 1020元 2010/06/21 150392500 2,4-二氯苯胺 2,4-Dichloroaniline 98% 250 GR 1146元
  • 海关编码:29214210
  • 方法一:由乙酰苯胺经氯化、水解而得。
  • 可燃性危险特性:明火可燃;燃烧释放有毒氯化物和氮氧化物烟雾;与氧化剂起作用
  • 外观性质:白色结晶。
  • 检测方法:HPLC,NMR
  • 下游产品:2,4-二氯苯硫酚 --> 环丙酸酰胺
  • 毒性分级:高毒
  • Sigma Aldrich:554-00-7(sigmaaldrich)
  • 急性毒性:口服-大鼠 LD50: 1600 毫克/公斤;口服-小鼠 LD50: 400 毫克/公斤
  • 见光或露置空气中逐渐变色。溶于醇、醚、有机溶剂和酸类,几乎不溶于水。有毒,最小致死量(猫,经口)173mg/kg。有刺激性。
  • MOL 文件:554-00-7.mol
  • 灭火剂:泡沫、二氧化碳、干粉、砂土。

系列性分类


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