Methacrylamide 甲基丙烯酰胺

CAS 79-39-0 MFCD00008018

化学结构图

79-39-0
SMILES: C=C(C)C(N)=O

化学属性

Mol. FormulaC4H7NO
Mol. Weight85.10
Melting Point106-110 °C
Density1.115
TSCAYes
Boiling Point215 °C at 760 mmHg
Solubility202 G/L (20 ºC)
Stability对湿度敏感
Flash Point215°C

别名和识别编码

Chemical NameMethacrylamide
Beilstein Registry Number605397
PubChem Substance ID87572190
CAS Number79-39-0
EC Number201-202-3
MDL NumberMFCD00008018
Synonym Methacrylamide {LY} Methacrylamide {} {LY} Methacrylamide {} {} {LY} Methacrylamide {} {} {} {LY} Methacrylamide {} {} {} {} {LY} Methacrylamide {} {} {} {} {} {LY} Methacrylamide {} {} {} {} {} {} {LY} Methacrylamide {} {} {} {} {} {} {} {LY} Methacrylamide {} {} {} {} {} {} {} {} {LY} Methacrylamide {} {} {} {} {} {} {} {} {} {LY} Methacrylamide {} {} {} {} {} {} {} {} {} {} {LY} Methacrylamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methacrylamide {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methacrylamide {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methacrylamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methacrylamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methacrylamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Methacrylamide {} {} {} {} {} {} {} {} {} {} {} {}
Reaxys-RN605397
Chemical Name Translation甲基丙烯酰胺
Wiswesser Line NotationZVY1&U1
LabNetwork Molecule IDLN00226604
Canonical SMILESCC(C(N)=O)=C
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分类

  • {SNA} Acrylamide and Methacrylamide, Acrylic Monomers, Materials Science, Monomers, Polymer Science
  • {SNA} Amides, Building Blocks, C2 to C7, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks
  • {uni_hamburg} no charge; amide; 1fragment
  • Acrylamide and Methacrylamide, Acrylic Monomers, Materials Science, Monomers, Polymer Science
  • {SNA} Acrylamide and Methacrylamide, Acrylic Monomers, Monomers, Polymer Science, 材料科学

产品应用

  • 有机合成。高分子化合物的合成。

相关文献及参考

  • Short: IV/20C
  • Short: EINECS
  • Beilstein:2(2)399

安全信息

Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P301+P312+P330
  • P305+P351+P338
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
WGK Germany1
GHS Symbol
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
Hazard Codes Xn
RTECSUC6475000
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Safety Statements
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition 2-8°C {LY} 2-8°C Store at room temperature {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°
Packing GroupIII
Hazard Class6.1(b)
UN Number 3263
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >6 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 45(10),74,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689

TYPE OF

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 451 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   47,179,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >6 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 45(10),74,1980

TYPE OF TEST            : TCLo -

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 2160 mg/kg
SEX/DURATION            : female 6-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - parturition
   Reproductive - Maternal Effects - other effects
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB91-208678

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1440 mg/kg
SEX/DURATION            : female 6-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB91-208678

其他信息

  • 图谱信息:甲基丙烯酰胺(79-39-0)红外图谱(IR2) 甲基丙烯酰胺(79-39-0)红外图谱(IR1) 甲基丙烯酰胺(79-39-0)核磁图( 1 HNMR) 甲基丙烯酰胺(79-39-0)质谱(MS)
  • 甲基丙烯酰胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30113183 甲基丙烯酰胺 250g 350元 2011/04/16 M0077 甲基丙烯酰胺 Methacrylamide 25G 139元 2011/04/16 M0077 甲基丙烯酰胺 Methacrylamide 500G 429元
  • 方法一:以氰化钠为原料与硫酸进行反应制得氢氰酸,氢氰酸再与丙酮反应生成丙酮氰醇,再与浓硫酸反应生成甲基丙烯酰胺硫酸盐,然后与氨水中和制得成品甲基丙烯酰胺。用氰化钠与硫酸反应制得氢氰酸。从氢氰酸开始制备甲基丙烯酰胺硫酸盐,其生产方法都与制甲基丙烯酸相同,得到的甲基丙烯酰胺硫酸盐经氨水中和、萃取、结晶、过滤、低温烘干制得成品。以氰化钠为原料生产甲基丙烯酰胺,每吨产品消耗氰化钠821kg、丙酮(≥98.5%)883kg、硫酸3440kg、液氨650kg。
  • 用途一:用于制取甲基丙烯酸甲酯
  • MOL 文件:79-39-0.mol
  • 用途三:有机合成。高分子化合物的合成。
  • 溶于乙醇,微溶于乙醚。有毒,半数致死量(小鼠,腹腔)300mg/kg。有刺激性。
  • 外观性质:白色或淡黄色固体。
  • MSDS 信息:甲基丙烯酰胺(79-39-0).msds
  • 用途二:甲基丙烯酰胺是生产甲基丙烯酸甲酯的中间体。
  • Alfa Aesar:甲基丙烯酰胺,98% Methacrylamide, 98%(79-39-0)
  • Sigma Aldrich:79-39-0(sigmaaldrich)
  • Acros Organics:甲基丙烯酰胺 Methacrylamide, extra pure, 98%(79-39-0)
  • TCI Shanghai:甲基丙烯酰胺 Methacrylamide,>;98.0%(T)(79-39-0)
  • 上游原料:氰化钠 --> 2-甲基丙烯酸 --> 氢氰酸 --> 丙酮氰醇
  • 下游产品:甲基丙烯酸乙酯 --> 亚甲基聚丙烯酰胺

系列性分类