Cetyltrimethylammonium Bromide 十六烷基三甲基溴化铵

CAS 57-09-0 MFCD00011772

化学结构图

57-09-0
SMILES: CCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]

化学属性

TSCAYes
Density1.013
SolubilitySoluble in water (36.4 g/l) at 20 °C, methanol (>200 g/l) at 20 °C, alcohol (Very soluble), acetone (Slightly soluble), and chloroform. Insoluble in ether, benzene, and diethyl ether.
Flash Point244°(471°F)
Stability易吸潮
Mol. FormulaC19H42BrN
Mol. Weight364.45
Appearance white solid
Melting Point248-251

别名和识别编码

Chemical NameCetyltrimethylammonium Bromide
Synonym ######## 1-hexadecyltrimethylammonium bromide 1-hexadecyltrimethylammonium chloride BCTA CETRIMIDE CETRIMIDE PER USP CTAB CTAOH CTMB Cetavlon Cetrimonium (bromide) Cetrimonium (bromide)(Reagent for Ion-Pair Chromatography,99%) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
PubChem Substance ID5974
EC Number200-311-3
Beilstein Registry Number3598189
Reaxys-RN3598189
Merck Number2025
Chemical Name Translation十六烷基三甲基溴化铵
Wiswesser Line Notation16K1&1&1 &Q &E
LabNetwork Molecule IDLN00194021
InChIInChI=1S/C19H42N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1
MDL NumberMFCD00011772
CAS Number57-09-0
Canonical SMILESCCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
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分类

  • {SNA} Acidic Ion Pair Reagents (Anionic),
  • {SNA} cationic
  • {SA} Alpha Sort, Alphabetic, Analytical Standards, Analytical/Chromatography, Bromo, Cationic Detergents, Cell Culture, Chemical Class, Chromatography, Detergents,
  • {SNA} Alpha Sort, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Biochemicals and Reagents, Bromo, Cationic Detergents, Cell Culture, Chemical Class, Chromatography, Detergents, Detergents A to M, Detergents by Applications, Diagnostic Applications, Drug Delivery-Liposomes,

产品应用

  • A cationic detergent used in the isolation of high molecular weight DNA.

相关文献及参考

  • Merck:14,2025 Beilstein: 4,IV,819
  • Merck:14,2025
  • O-Alkylation of alcohols and phenols; see 2,6-Dimethyl­phenol, A11947. Surfactant-assisted permanganate oxidations: Can. J. Chem., 67, 1381 (1989). Reduction of alkyl halides to alkanes using zinc powder in micelles: Synth. Commun., 19, 1649 (1989). Control of ortho-para ratio in the bromination of anilines: Tetrahedron Lett., 30, 6209 (1989). Also facilitates ligand-free palladium salt-catalyzed Heck and Suzuki cross-coupling reactions in water: Tetrahedron Lett., 46, 3357 (2005).
  • Short: III/31a
  • Yu, H.-h., et al.: Gongneng Cailiao, 42,?2005 (2011),
  • Surfactant-type catalyst (see Appendix 2) with many applications:

安全信息

GHS Symbol
WGK Germany3
Hazard Codes 9
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RTECSBQ7875000
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P312
  • P301+P312+P330
  • P301+P330+P331
  • P302+P350
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P303+P361+P353
  • P304+P340
  • P305+P351+P338
  • P307+P311
  • P308+P313
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医，如果你觉得不舒服
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
UN Number 3077 UN 3077 9/PG 3 UN3077
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
  • S39 Wear eye/face protection 戴眼睛/面孔保护装置；
  • S57 Use appropriate containment to avoid environmental contamination 使用适当容器避免环境污染；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R48/22
  • R50 Very toxic to aquatic organisms 对水生生物极毒
Storage condition 2-8°C, protect from light Hygroscopic Store at RT. Store at room temperature, keep dry and cool 充氩保存 密封保存。 易吸潮、密封保存。
Packing GroupIII
Hazard Class9 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 410 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKYUA6 Yakkyoku.  Pharmacy.  (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo,
   Japan)  V.1-    1950-  Volume(issue)/page/year: 31,471,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,210,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College
   Science Pub., 1969  Volume(issue)/page/year: 5,40,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rode

TYPE OF TEST

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,210,1966

{hazard

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 35 mg/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 13,331,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 35 mg/kg
SEX/DURATION            : female 12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 13,331,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 10500 ug/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - mus

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 10500 ug/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 13,331,1975

其他信息

  • Sigma Aldrich:57-09-0(sigmaaldrich)
  • 方法二:由十六醇经溴素溴化后与三甲胺反应生成季铵盐。
  • 用途六:催化剂,乳化剂,消毒剂,杀菌基,抗静电剂等。比色测定或光度测定锑和锡。肠内葡萄糖吸收抑制剂。芳烃还原和烯环氧化时的相转移催化剂。表面活性剂。杀菌剂。消毒剂。
  • MSDS 信息:Hexadecyl trimethyl ammonium bromide(57-09-0).msds
  • 是一种季铵盐。有吸湿性。有酸性溶液稳定。水中溶解度: 13 g/L (20°C) ，易溶于乙醇和甲醇(>200 g/L ，20°C), 微溶于丙酮，几乎不溶于乙醚、氯仿和苯。半数致死量(大鼠，静脉)44mg/kg。对眼睛、呼吸系统和皮肤有刺激性。
  • TCI Shanghai:十六烷基三甲基溴化铵 Hexadecyltrimethylammonium Bromide,>;98.0%(T
  • Acros Organics:十六烷基三甲基溴化铵/CTMAB Hexadecyltrimethylammonium bromide, 99+%(57-09-0)
  • MOL 文件:57-09-0.mol
  • 储运特性:库房低温, 通风, 干燥; 与食品原料分开存放
  • {Ch
  • 图谱信息:十六烷基三甲基溴化铵(57-09-0)核磁图( 1 HNMR) 十六烷基三甲基溴化铵(57-09-0)核磁图( 13 CNMR) 十六烷基三甲基溴化铵(57-09-0)红外图谱(IR2) 十六烷基三甲基溴化铵(57-09-0)Raman光谱 十六烷基三甲基溴化铵(57-09-0)红外图谱(IR1)
  • 上游原料:溴 --> 三甲胺 --> 1-十六烷醇 --> 溴代十六烷 --> 胺丙酮
  • 用途一:具有优良的渗透、柔化、乳化、抗静电、生物降解性及杀菌等性能。化学稳定性好，耐热、耐光、耐压、耐强酸强碱。用作天然、合成橡胶、硅油和沥青乳化剂；合成纤维、天然纤维和玻璃纤维的抗静电剂、柔软剂；护发素的调理剂。
  • F:3
  • 用途二:用作肠内葡萄糖吸收抑制剂、表面活性剂
  • color:white
  • 敏感性:Hygroscopic
  • 十六烷基三甲基溴化铵价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30037416 十六烷基三甲基溴化铵;鲸蜡烷三甲基溴化铵 100g 56.2元 2011/04/16 H0081 十六烷基三甲基溴化铵 Hexadecyltrimethylammonium Bromide 25G 190元 2011/04/16 H0081 十六烷基三甲基溴化铵 Hexadecylt
  • Alfa Aesar:（1－十六烷基）三甲基溴化铵,98% (1-Hexadecyl)trimethylammonium bromide, 98%(57-09-0)
  • 用途五:用于有机合成，也可作为阳离子表面活性剂，用作杀菌剂，配制含漱剂、消毒剂，肠内葡萄糖吸收抑制剂。该品
  • 类别:农药
  • 检测方法:T,NMR
  • 下游产品:二苯基乙炔 --> 精吡氟禾草灵 --> 1-[(3-吡啶)甲基]哌嗪 --> 交联壳聚糖缩水杨醛螯合树脂 --> 亮氨酸氨肽酶
  • 灭火剂:泡沫、雾状水、二氧化碳、砂土
  • 用途四:本品为阳离子表面活性剂。可用作杀菌剂，配制含漱水、消毒剂、肠内葡萄吸收抑制剂。亦可作胶束增溶分光光度测定试剂。
  • 方法一:将三甲胺水溶液投入汽化釜中，加热至沸，产生的三甲胺气体经干燥后用丙酮吸收，在吸收塔中生成三甲胺丙酮溶液，使其进入季铵化釜。然后在搅拌下滴加溴代十六烷，二者摩尔比为1.10︰1。滴加过程中保温30～40℃，滴毕后再保温搅拌1 h。冷却结晶，得粗品，用丙酮洗涤，甩干，干燥得产品。
  • 急性毒性:口服- 大鼠 LD50: 410 毫克/ 公斤;静脉- 小鼠 LD50: 32 毫克/ 公斤

系列性分类

  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. Anionic Detergents - Detergents
  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. Cationic Detergents - Detergents
  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. Cationic Detergents - Detergents
  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. BioUltra Detergents - Detergents
  1. Chemical Synthesis 化学合成
  2. Synthetic Reagents 合成试剂
  3. Phase Transfer Catalysts 相转移催化剂
  1. Chemical Synthesis 化学合成
  2. Synthetic Reagents 合成试剂
  3. Phase Transfer Catalysts 相转移催化剂
  4. Ammonium Salts - Phase Transfer Catalysts
  1. Chemical Synthesis 化学合成
  2. Synthetic Reagents 合成试剂
  3. Phase Transfer Catalysts 相转移催化剂
  4. Ammonium Salts - Phase Transfer Catalysts
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Nitrogen Compounds 氮化合物
  5. Amine Salts - Nitrogen Compounds
  1. Life Science 生命科学
  2. Plant Biotechnology 植物生物技术
  3. Plant Molecular Biology - Plant Biotechnology
  4. Plant Nucleic Acid Purification - Plant Molecular Biology
  5. Reagents - Plant Nucleic Acid Purification
  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Protein Structural Analysis - Proteomics
  4. X-Ray Crystallography - Protein Structural Analysis
  5. Optimization Reagents - X-Ray Crystallography
  1. Analytical & Chromatography 分析化学与色谱
  2. HPLC
  3. Buffers & Reagents - HPLC
  4. Ion Pair Reagents 离子对试剂
  5. Ion Pair Reagents - Anionic - Ion Pair Reagents
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Reagents
  3. Chromatography Reagents & Solvents - Analytical Reagents
  4. Ion Pair Reagents - Chromatography Reagents & Solvents
  5. Acidic Ion Pair Reagents (Anionic) - Ion Pair Reagents
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Signal Transduction Research Tools - Cell Signaling and Neuroscience
  5. Cell Lysis Reagents - Signal Transduction Research Tools
  6. Detergents - Cell Lysis Reagents
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Chemicals by Class 化学分类法
  4. Quaternary Ammonium Compounds 季铵化合物
  1. Functional Group 官能团索引
  2. quaternary ammonium salt
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Signal Transduction Research Tools
  5. Cell Lysis Reagents
  1. Surfactants for Nano Synthesis
  2. Nanomaterials
  1. Nanomaterials
  2. Nanomaterials