CAS 1185-53-1 MFCD00012590-Tri(hydroxymethyl)aminomethane hydrochloride 三(羟甲基)氨基甲烷盐酸盐 -LabNovo

Tri(hydroxymethyl)aminomethane hydrochloride 三(羟甲基)氨基甲烷盐酸盐

CAS 1185-53-1 MFCD00012590

化学结构图

SMILES: Cl.NC(CO)(CO)CO

化学属性

Mol. Formula	C4H12ClNO3
Mol. Weight	157.60
Density	1.05 g/mL at 20 °C
Melting Point	150-152 °C
TSCA	Yes
Solubility	可溶
Appearance	crystalline
Stability	对湿度敏感
Boiling Point	225 °C at 760 mmHg

别名和识别编码

Chemical Name	Tri(hydroxymethyl)aminomethane hydrochloride
Synonym	THAM (hydrochloride) {LY} THAM (hydrochloride) {} {LY} THAM (hydrochloride) {} {} {LY} THAM (hydrochloride) {} {} {} {LY} THAM (hydrochloride) {} {} {} {} {LY} THAM (hydrochloride) {} {} {} {} {} {LY} THAM (hydrochloride) {} {} {} {} {} {} {LY} THAM (hydrochloride) {} {} {} {} {} {} {} {LY} THAM (hydrochloride) {} {} {} {} {} {} {} {} {LY} THAM (hydrochloride) {} {} {} {} {} {} {} {} {} {LY} THAM (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {LY} THAM (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} THAM (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {LY} THAM (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} THAM (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} THAM (hydrochloride) {} {} {} {} {} {} {} {}
MDL Number	MFCD00012590
CAS Number	1185-53-1
EC Number	214-684-5
Beilstein Registry Number	3675235
PubChem Substance ID	87576591
Reaxys-RN	3675235
Chemical Name Translation	三(羟甲基)氨基甲烷盐酸盐
Merck Number	14,9651
LabNetwork Molecule ID	LN00191878
Canonical SMILES	OCC(CO)(N)CO.[H]Cl

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产品应用

For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode;For Tris buffers, pH increases about 0.03 unit/°C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.

安全信息

Signal word Warning

GHS Symbol

WGK Germany1

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36 Wear suitable protective clothing 穿戴适当的防护服；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P281 Use personal protective equipment as required. 使用所需的个人防护装备。
P302+P350
P302+P352+P332+P313+P362+P364
P305+P351+P338
P305+P351+P338+P337+P313
P332+P313
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H335 May cause respiratory irritation 可能导致呼吸道刺激

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Storage condition Store at room temperature, keep dry and cool {LY} Store at room temperature, keep dry and cool {} {LY} Store at room temperature, keep dry and cool {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {}

Hazard Codes Xi

其他信息

三(羟甲基)甲基甘氨酸价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 62022632 三（羟甲基）甲基甘氨酸 5g 41元 2011/04/16 T0682 麦黄酮[生物研究用Good's缓冲液中的成分] Tricine [Good's buffer component for biological research] 250G 2140元 2011/04/16 T0682 麦黄酮[生物研究用Good's缓冲液中的成分] Tricine [Good's buffer component for biological research] 25G 312元
TCI Shanghai:三(羟甲基)甲基甘氨酸[生物研究用Good's缓冲液中的成分] N-[Tris(hydroxymethyl)methyl]glycine [Good's buffer component for biological research],>;99.0%(T)(5704-04-1)
外观性质:白色晶体粉末，溶于水。pH range： 7.4 - 8.8 pKa (25 °C)： 8.1 熔点：182-184℃
F:3
Alfa Aesar:三(羟甲基)甲基甘氨酸,98+% Tricine, 98+%(5704-04-1)
Acros Organics:N-(三羟甲基)甲基甘氨酸 Tricine, for biochemistry, 99+%(5704-04-1)
溶于水
useful pH range 7.0 - 9.0 pKa (25 °C) 8.1
color:clear colorless (40 % (w/w) in H 2 O) solution
用途一:生物缓冲剂，用在分离低分子量多肽的场合。
Sigma Aldrich:5704-04-1(sigmaaldrich)
MOL 文件:5704-04-1.mol