4-(2-Chloroethyl)morpholine hydrochloride N-(2-氯乙基)吗啉盐酸盐

CAS 3647-69-6 MFCD00012797

化学结构图

3647-69-6
SMILES: Cl.ClCCN1CCOCC1

化学属性

Mol. FormulaC6H13Cl2NO
Mol. Weight186.08
Melting Point180-185°C
TSCAYes
Solubility可溶
Appearance 类白色结晶粉末,熔点184-186℃。

别名和识别编码

Chemical Name4-(2-Chloroethyl)morpholine hydrochloride
Synonym 4-(2-Chloroethyl)morpholine hydrochloride {LY} 4-(2-Chloroethyl)morpholine hydrochloride {} {LY} 4-(2-Chloroethyl)morpholine hydrochloride {} {} {LY} 4-(2-Chloroethyl)morpholine hydrochloride {} {} {} {LY} 4-(2-Chloroethyl)morpholine hydrochloride {} {} {} {} {LY} 4-(2-Chloroethyl)morpholine hydrochloride {} {} {} {} {} {LY} 4-(2-Chloroethyl)morpholine hydrochloride {} {} {} {} {} {} {LY} 4-(2-Chloroethyl)morpholine hydrochloride {} {} {} {} {} {} {} {LY} 4-(2-Chloroethyl)morpholine hydrochloride {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {LY} 4-(2-Chloroethyl)morpholine hydrochloride {} {} {} {} {} {} {} {} {} {LY} 4-(2-Chloroethyl)morpholine hydrochloride {} {} {} {} {} {} {} {} {} {} {LY} 4-(2-Chloroethyl)morpholine hydrochloride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-(2-Chloroethyl)morpholine hydrochloride {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-(2-Chloroethyl)morpholine hydrochloride {} {} {} {} {} {} {} {} {} {} {
CAS Number3647-69-6
PubChem Substance ID77210
EC Number222-881-2
Beilstein Registry Number3684083
MDL NumberMFCD00012797
Reaxys-RN3684083
Chemical Name TranslationN-(2-氯乙基)吗啉盐酸盐
InChIKeyNBJHDLKSWUDGJG-UHFFFAOYSA-N
Wiswesser Line NotationT6N DOTJ A2G &GH
LabNetwork Molecule IDLN00008816
InChIInChI=1S/C6H12ClNO.ClH/c7-1-2-8-3-5-9-6-4-8;/h1-6H2;1H
Canonical SMILESClCCN1CCOCC1.[H]Cl
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分类

  • Building Blocks, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Morpholines/Thiomorpholines
  • {SNA} Building Blocks, C4 to C10, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Morpholines/Thiomorpholines

相关文献及参考

  • Beil. 27 ,IV,24
  • FT-IR 1 (1), 383:C / FT-IR 2 (1), 597:A / IR-Spectra (3), 226:H / IR-Spectra (2), 203:C / NMR-Reference 2 (1), 336:D / RegBook 1 (1), 403:F / Sax 6 , 719 / Structure Index 1 , 58:A:4

安全信息

GHS Symbol
WGK Germany2
Hazard Codes 8 T
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H312 Harmful in contact with skin 皮肤接触有害
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECSQE0260000
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P303+P361+P353
  • P303+P361+P353+P310+P363
  • P304+P340
  • P305+P351+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
UN Number 2923
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
Risk Statements
  • R21 Harmful in contact with skin 与皮肤接触有害
  • R25 Toxic if swallowed 吞咽有毒
  • R34 Causes burns 会导致灼伤
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
Storage condition 2-8°C, sealed storage, away from moisture {LY} 2-8°C, sealed storage, away from moisture Hygroscopic {} {LY} 2-8°C, sealed storage, away from moisture {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away f
Packing GroupIII
Hazard Class8/6.1 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 161 mg/kg
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   CANCAR Cancer (Philadelphia).  (Lippincott/Harper, Journal Fulfillment
   Dept., 2350 Virginia Ave., Hagerstown, MD 21740)  V.1-    1948-
   Volume(issue)/page/year: 2,1075,1949

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 44 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,33,1981

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 21500 nmol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,11,1981

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 100 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,11,1981

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 21500 nmol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,11,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 150 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   CANCAR Cancer (Philadelphia).  (Lippincott/Harper, Journal Fulfillment
   Dept., 2350 Virginia Ave., Hagerstown, MD 21740)  V.1-    1948-
   Volume(issue)/page/year: 2,1075,1949

其他信息

  • MSDS 信息:2-Morpholinoethyl chloride hydrochloride(3647-69-6).msds
  • 可燃性危险特性:可燃, 火场释放有毒氯化物, 氮氧化物烟雾
  • 用途一:医药中间体。
  • 毒性分级:中毒
  • 储运特性:库房低温通风干燥
  • 爆炸物危险特性:0
  • 刺激数据:0
  • 图谱信息:N-(2-氯乙基)吗啉盐酸盐(3647-69-6)质谱(MS) N-(2-氯乙基)吗啉盐酸盐(3647-69-6)红外图谱(IR1) N-(2-氯乙基)吗啉盐酸盐(3647-69-6)核磁图( 1 HNMR) N-(2-氯乙基)吗啉盐酸盐(3647-69-6)红外图谱(IR2)
  • 急性毒性:腹腔-小鼠 LD50: 161 毫克/公斤
  • 敏感性:Hygroscopic
  • 方法一:吗啉与环氧乙烷加成制得吗啉乙醇，再与氯化亚砜进行氯化反应得到氯化乙基吗啉盐酸盐。
  • 上游原料:2-吗啉乙醇
  • 职业标准:0
  • 类别:有毒物质
  • Sigma Aldrich:3647-69-6(sigmaaldrich)
  • Alfa Aesar:4-（2-氯乙基）吗啉盐酸盐,99% 4-(2-Chloroethyl)morpholine hydrochloride, 99%(3647-69-6)
  • N-(2-氯乙基)吗啉盐酸盐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C1106 N-(2-氯乙基)吗啉盐酸盐 4-(2-Chloroethyl)morpholine Hydrochloride 25G 156元 2014/06/02 C1106 N-(2-氯乙基)吗啉盐酸盐 4-(2-Chloroethyl)morpholine Hydrochloride 500G 1360元 2010/06/21 109200050 N-(2-氯乙基)吗啉盐酸盐 N-(2-Chloroethyl)morpholine hydrochloride 99% 5 GR 230元
  • TCI Shanghai:N-(2-氯乙基)吗啉盐酸盐 4-(2-Chloroethyl)morpholine Hydrochloride,>;97.0%(T)(3647-69-6)
  • MOL 文件:3647-69-6.mol
  • Acros Organics:N-(2-氯乙基)吗啉盐酸盐 N-(2-Chloroethyl)morpholine hydrochloride, 99%(3647-69-6)
  • 下游产品:4-(2-吗啉-4-基-乙氧基)苯甲酸
  • 灭火剂:水, 二氧化碳, 泡沫, 沙土
  • 海关编码:29349990

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Isoxazoles 异恶唑
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Morpholines/Thiomorpholines 吗啉/硫吗啉
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Halogenated Heterocycles 卤代杂环
  5. Morpholines/Thiomorpholines - Halogenated Heterocycles
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Halogenated Heterocycles 卤代杂环
  5. Morpholines/Thiomorpholines - Halogenated Heterocycles
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Morpholines/Thiomorpholines 吗啉/硫吗啉
  5. C4 to C10 - Morpholines/Thiomorpholines
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Halogenated Heterocycles 卤代杂环
  5. Isoxazoles