Triethyloxonium tetrafluoroborate 三乙基氧鎓四氟硼酸盐

CAS 368-39-8 MFCD00044423

化学结构图

368-39-8
SMILES: CC[O+](CC)CC.F[B-](F)(F)F

化学属性

Mol. FormulaC6H15BF4O
Mol. Weight189.99
Density1.328
TSCAYes
Melting Point96-97°C
Solubility起反应
Stability对湿度敏感

别名和识别编码

Chemical NameTriethyloxonium tetrafluoroborate
MDL NumberMFCD00044423
CAS Number368-39-8
EC Number206-705-1
Beilstein Registry Number3598090
PubChem Substance ID2723982
Synonym Triethyloxonium tetrafluoroborate {LY} Triethyloxonium tetrafluoroborate {} {LY} Triethyloxonium tetrafluoroborate {} {} {LY} Triethyloxonium tetrafluoroborate {} {} {} {LY} Triethyloxonium tetrafluoroborate {} {} {} {} {LY} Triethyloxonium tetrafluoroborate {} {} {} {} {} {LY} Triethyloxonium tetrafluoroborate {} {} {} {} {} {} {LY} Triethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Triethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {LY} Triethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {} {LY} Triethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {} {} {LY} Triethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Triethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {} {} {} {} {LY} Triethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Triethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {} {}
Merck Number5796
Chemical Name Translation三乙基氧鎓四氟硼酸盐
Reaxys-RN3598090
LabNetwork Molecule IDLN00011356
InChIInChI=1S/C6H15O.BF4/c1-4-7(5-2)6-3;2-1(3,4)5/h4-6H2,1-3H3;/q+1;-1
Canonical SMILESCC[O+](CC)CC.F[B-](F)(F)F
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分类

  • {SNA} Alkyl Transfer, C-X Bond Formation (Non-Halogen), Chemical Synthesis, Synthetic Reagents

产品应用

  • 强力乙基化剂; 酸的酯化;蛋白质羧基修饰。

相关文献及参考

  • Trialkyloxonium salts, also known as Meerwein's salts, are powerful alkylating agents: Chem. Ber., 89, 209, 2060 (1956). For a brief feature on uses of Meerwein's salts in synthesis, see: Synlett, 195 (2004).
  • Likewise, N-alkylation of nitriles results in their activation to reduction by triethylsilane to give aldehydes, via the imines: Synthesis, 420 (1973); J. Chem. Soc., Chem. Commun., 45 (1974); J. Org. Chem., 46, 602 (1981).
  • For further reactions of trialkyloxonium salts, see Trimethyl­oxonium tetrafluoroborate, A15175.
  • In combination with a hindered base, e.g. N-Ethyl­diisopropyl­amine, A11801, is a convenient reagent for the conversion of carboxylic acids to their ethyl esters by O-alkylation: Tetrahedron Lett., 4741 (1971); Org. Synth. Coll., 6, 576 (1988).
  • Merck: 14,5796 Beilstein: 1,IV,1322
  • Merck: 14,5796
  • Secondary and tertiary amides are O-alkylated to give immonium salts and imino ethers, respectively. Reduction with borohydride provides an effective amide to amine conversion: Tetrahedron Lett., 61 (1968):

安全信息

RTECSRR4584700
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S22 Do not breathe dust 不要吸入粉尘;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Packing GroupII
UN Number 3261 3265
Risk Statements
  • R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
  • R37 Irritating to respiratory system 刺激呼吸道
  • R14 Reacts violently with water 遇水会猛烈反应
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R34 Causes burns 会导致灼伤
Storage condition 2-8°C, stored under nitrogen, away from moisture {LY} 2-8°C, stored under nitrogen, away from moisture <0°C <;0 Moisture Sensitive {} {LY} 2-8°C, stored under nitrogen, away from moisture {} {} {LY} 2-8°C, stored under nitrogen, away from moisture {} {} {} {LY} 2-8°C, stored under nitrogen, away from moisture {} {} {} {} {LY} 2-8°C, stored under nitrogen, away from moisture {} {} {} {} {} {LY} 2-8°C, stored under nitrogen, away from moisture {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen, away from moisture {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen, away from moisture {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen, away from moisture {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen, away from moisture {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen, away from moisture {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen, away from moisture {} {} {} {} {} {} {} {} {} {} {} {}
WGK Germany3
Precautionary statements
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P403+P233
  • P305+P351+P338+P310
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P301+P330+P331+P310
  • P303+P361+P353
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P304+P340
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H351 Suspected of causing cancer 怀疑致癌
  • H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
GHS Symbol
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Signal word
Hazard Codes C
Hazard Class8

其他信息

  • F:3-10-16-21
  • MSDS 信息:Triethyloxonium tetrafluoroborate(368-39-8).msds
  • Sigma Aldrich:368-39-8(sigmaaldrich)
  • 三乙基氧翁四氟硼酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 T1606 三乙基氧四氟硼酸盐(15%的二氯甲烷溶液,约1mol/L)[乙基化剂] Triethyloxonium Tetrafluoroborate (15% in Dichloromethane, ca. 1mol/L) [Ethylating Reagent] 100ML 941元 2010/06/21 175111000 三乙基氧翁四氟硼酸 Triethyloxonium tetrafluoroborate , 1M solution in methylene chloride 100 ML 1077元 2010/06/21 429161000 三乙基氧翁四氟硼酸 Triethyloxonium tetrafluoroborate , 1M solution in methylene chloride, AcroSeal® 100 ML 1242元
  • Acros Organics:三乙基氧鎓四氟硼酸 Triethyloxonium tetrafluoroborate, 1M solution in methylene chloride(368-39-8)
  • Hazard Note:Corrosive
  • TCI Shanghai:三乙基氧四氟硼酸盐(15%的二氯甲烷溶液,约1mol/L)[乙基化剂] Triethyloxonium Tetrafluoroborate (15% in Dichloromethane, ca. 1mol/L) [Ethylating Reagent](368-39-8)
  • Alfa Aesar:三乙基氧四氟硼酸盐,95%,stab.with3-5%diethylether Triethyloxonium tetrafluoroborate, 95%, stab. with 3-5% diethyl ether(368-39-8)
  • 用途一:强力乙基化剂; 酸的酯化;蛋白质羧基修饰。
  • 海关编码:29420000
  • MOL 文件:368-39-8.mol
  • 敏感性:Moisture Sensitive

系列性分类


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