(S)-(+)-Epichlorohydrin (S)-(+)-环氧氯丙烷

CAS N/A MFCD00077760

化学结构图

N/A
SMILES:

化学属性

Mol. FormulaC3H5ClO
Mol. Weight92.52
Refractive index1.4370 to 1.4390
Boiling Point114
Density1.183
Flash Point34°C(lit.)
TSCANo
Autoignition Point1421 °F
Vapor Density3.2 (vs air)
Vapor Pressure12.5 mmHg ( 20 °C)

别名和识别编码

Chemical Name(S)-(+)-Epichlorohydrin
CAS Number67843-74-7
Synonym (S)-(+)-Epichlorohydrin (S)-(Chloromethyl)oxirane
Beilstein Registry Number17(5)1,21
PubChem Substance ID87569779
MDL NumberMFCD00077760
Reaxys-RN1420784
EC Number250-023-7
Chemical Name Translation(S)-(+)-环氧氯丙烷
LabNetwork Molecule IDLN00213352
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分类

  • Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Epoxides, Organic Building Blocks
  • {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Epoxides, Organic Building Blocks

产品应用

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相关文献及参考

  • Bioorg. Med. Chem. Lett. 14 , 973, (2004) 摘要
  • Munakatam, R. et al. J. Am. Chem. Soc. 126 , 11254, (2004) 摘要
  • Munakata, R. et al. J. Am. Chem. Soc. 125 , 14722, (2003) 摘要
  • Burova, S. A.; McDonald, F. E. J. Am. Chem. Soc. 126 , 2495, (2004) 摘要
  • Beil. 17 ,V,1,21
  • Beilstein:17(5)1,21
  • Romano, K.P. et al.: Chem. Res. Toxicol., 20, 832 (2007); Smyth, H.F., et al.: J. Ind. Hyg. Toxicol., 30, 63 (1948);

安全信息

GHS Symbol
WGK Germany3
Hazard Codes T
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H350 May cause cancer 可能致癌
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H301+H311+H331
  • H331 Toxic if inhaled 吸入中毒
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H301 Toxic if swallowed 吞食有毒
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSRR0427100
Precautionary statements
  • P305+P351+P338+P310
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P304+P340+P310
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P403+P233
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P303+P361+P353
  • P308+P313
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P301+P330+P331+P310
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P301+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P308+P311
  • P241+P242+P243
Signal word
UN Number UN2023 2023
Risk Statements
  • R10 Flammable 易燃
  • R45 May cause cancer 可能致癌
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R34 Causes burns 会导致灼伤
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
Packing GroupII
Storage condition 储存温度 2-8℃
Hazard Class6.1/3
TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 298,197,1993

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 800 nmol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 298,197,1993

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 298,197,1993

系列性分类