4-Carboxyphenylboronic Acid 4-羧基苯硼酸

CAS 14047-29-1 MFCD00151801

化学结构图

14047-29-1
SMILES: O=C(O)c1ccc(B(O)O)cc1

化学属性

Mol. FormulaC7H7BO4
Mol. Weight165.94
Melting Point220
TSCANo
Density1.422
Appearance white to off-white pwdr.
Danger-Level-
pH-:-
Redox-

别名和识别编码

Chemical Name4-Carboxyphenylboronic Acid
CAS Number14047-29-1
Alfabeta NameCARBOXYPHENYLBORONICACID 4-
MDL NumberMFCD00151801
Synonym 4-(Dihydroxyboronyl)benzoic acid 4-(Dihydroxyboryl)benzoic acid, 4-Boronobenzoic acid 4-Carboxybenzeneboronic acid 4-Carboxylphenylboronic acid 4-Hydroxycarbonylphenyl boronic acid 4-硼酸苯甲酸 Benzoic acid, p-borono- NSC 221170 p-Boronobenzoic acid p-Carboxybenzeneboronic acid p-Carboxyphenylboronic acid
Beilstein Registry Number3031088
PubChem Substance ID87566365
Reaxys-RN3031088
EC Number000-000-0
Chemical Name Translation4-羧基苯硼酸
InChIKeyJCGNPQHAXBIDLH-UHFFFAOYSA-N
Wiswesser Line NotationVHOR DBQQ
LabNetwork Molecule IDLN00159452
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分类

  • {SNA} Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Monosubstituted Aryl Boronic Acids, Organometallic Reagents
  • Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Monosubstituted Aryl Boronic Acids, Organometallic Reagents

相关文献及参考

  • 1. R. Pelton, et al., , Borate Binding to Polyol-Stabilized Latex Langmuir 27 , 2118-2123, (2011) 摘要
  • 2. B. Vercelli, et al., , Self-assembled multilayers of CdSe nanocrystals and carboxylate-handled phenylene-based molecules: optical, electrochemical and photoconductive properties J. Mater. Chem. 21 , 8645-8652, (2011)
  • 3. Y. Koyama, et al., , Polymer architectures assisted by dynamic covalent bonds: synthesis and properties of boronate-functionalized polyrotaxane and graft polyrotaxane Polymer J. , (2011)
  • 4. W. Chen, et al., , Solution Properties of Polyvinylamine Derivatized with Phenylboronic Acid Macromolecules 42 , 1300-1305, (2009)
  • 5. D. J. Kutscher and J. Bettmer, , Absolute and Relative Protein Quantification with the Use of Isotopically Labeled p -Hydroxymercuribenzoic Acid and Complementary MALDI-MS and ICPMS Detection Anal. Chem. 81 , 9172-9177, (2009) 摘要
  • 6. C. Lin, et al., , Poly-silicon nanowire field-effect transistor for ultrasensitive and label-free detection of pathogenic avian influenza DNA Biosens. Bioelectron. 24 , 3019-3024, (2009) 摘要
  • Daze, K. D.; et al., Synthesis of New Trisulfonated Calix[4]arenes Functionalized at the Upper Rim, and Their Complexation with the Trimethyllysine Epigenetic Mark Org. Lett. 6th ed., 14 , 1512-1515, (2012) 摘要
  • Tang, R.; Lee, H.; Achilefu, S. , Induction of pH Sensitivity on the Fluorescence Lifetime of Quantum Dots by NIR Fluorescent Dyes J. Am. Chem. Soc. 10th ed., 134 , 4545-4548, (2012) 摘要
  • Dieudonne-Vatran, A.; Azoulay, M.; Florent, J-C. , A new access to 3-substituted-1(2H)-isoquinolone by tandem palladium-catalyzed intramolecular aminocarbonylation annulation Org. Biomolecular Chem. 13th ed., 10 , 2683-2691, (2012)
  • Xu, H-J.; et al. , Chan-Lam-Type S-

安全信息

Warnings IRRITANT
WGK Germany2
RTECSCY8925000
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P302+P352+P332+P313+P362+P364
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P332+P313
  • P305+P351+P338+P337+P313
  • P302+P350
  • P337+P313
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1740 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   14KTAK "Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New
   York, John Wiley & Sons, Inc., 1964  Volume(issue)/page/year: -,693,1964

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APYPAY Acta Physiologica Polonica.  (Karger-Libri, POB CH-4009, Warszawa,
   Switzerland) V.1-41, 1950-90.  Volume(issue)/page/year: 12,173,1961

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