2-Mercaptopyridine N-oxide sodium salt 2-巯基吡啶-1-氧化钠盐

CAS N/A MFCD01941547

化学结构图

N/A
SMILES:

化学属性

Mol. FormulaC5H4NNaOS
Mol. Weight149.14
Density1.22
Melting Point-30--25°C
TSCAYes
Boiling Point109°C
Solubility54.7 G/100 ML
Appearance 白色或类白色粉末,易溶于水和乙醇等有机溶剂。
Stability易吸潮

别名和识别编码

Chemical Name2-Mercaptopyridine N-oxide sodium salt
MDL NumberMFCD01941547
CAS Number3811-73-2
EC Number223-296-5
Beilstein Registry Number4026050
Synonym N-氧-2-巯基吡啶钠 2-巯基吡啶-N-氧化物 钠盐 溶液 SODIUM PYRITHIONE 2-巯基吡啶氧化物钠盐 吡硫鎓钠 奥麦丁钠 2-PYRIDINETHIOL-1-OXIDE SODIUM SALT Pyrithione sodium salt 吡啶硫酮 钠盐 PYRITHIONE SODIUM SALT 2-巯基吡啶-1-氧化钠盐 Sodium, (2-pyridylthio)-, N-oxide 2-MERCAPTOPYRIDINE N-OXIDE SODIUM SALT MERCAPTOPYRIDINE N-OXIDE SODIUM SALT 2-巯基吡啶-1-氧化物 钠盐 2-Pyridinethiol-1-oxide, sodium salt; N-Hydroxy-2-pyridinethione, sodium salt; Sodium omadine monohydrate; Sodium omadine 1-羟基-2-吡啶硫酮 钠盐 2-硫代-1-氧化吡啶 钠盐
PubChem Substance ID354334541
Merck Number7994
Chemical Name Translation2-巯基吡啶-1-氧化钠盐
Wiswesser Line NotationT6NJ AO BS &-NA-
Reaxys-RN3598404
LabNetwork Molecule IDLN00222924
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分类

  • {SNA} Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antibiotics by Application, Antifungal, Biochemicals and Reagents, Interferes with Cell Membrane Permeability (Ionophores), Mechanism of Action, Preservatives and Disinfectants, Spectrum of Activity
  • {SA} Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antibiotics by Application, Antifungal, Interferes with Cell Membrane Permeability (Ionophores), Mechanism of Action, Preservatives and Disinfectants, Spectrum of Activity
  • {SNA} Building Blocks, C5, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines
  • {SNA} Antibiotics A to Z, Antibiotics G

产品应用

  • 碳酸酯和这种氧化物会发生脱羧化径向链反应。

相关文献及参考

  • Beilstein: 21,V,7,151

安全信息

Signal word
GHS Symbol
WGK Germany3
Safety Statements
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Risk Statements
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSUT9000000
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter dust mask type N95 (US), Eyeshields, Gloves
Storage condition Hygroscopic
Hazard Codes Xn Xn,Xi Xi
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CBCCT* "Summary Tables of Biological Tests," National Research Council
   Chemical-Biological Coordination Center.  (National Academy of Science
   Library, 2101 Constitution Ave., NW, Washington, DC 20418)
   Volume(issue)/page/year: 7,693,1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 370 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 4,883,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 870 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 4,883,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 428 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 4,883,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Int

其他信息

  • 抗菌谱:吡硫钠的抗菌谱如下: 试验微生物量/~106CFU·ml -1 MIC/μg·ml -1 金黄色葡萄球菌 粪链球菌 大肠埃希氏菌 鼠伤寒沙门氏菌 绿脓杆菌 白色念珠菌 须疮小芽胞癣菌 黑曲霉菌 点青霉菌 1 2 8 64 512 4 0.5 2 2
  • 吡硫钠价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 M0632 2-巯基吡啶N-氧化钠盐(40%的水溶液,约3.3mol/L) 2-Mercaptopyridine N-Oxide Sodium Salt (40% in Water, ca. 3.3mol/L) 25G 169元 2014/06/02 M0632 2-巯基吡啶N-氧化钠盐(40%的水溶液,约3.3mol/L) 2-Mercaptopyridine N-Oxide Sodium Salt (40% in Water, ca. 3.3mol/L) 500G 1200元 2010/06/21 257740025 吡硫钠 2-Mercaptopyridine-N-oxide, sodium salt , 40 w/w % aqueous solution 2.5 LT 10409元
  • MOL 文件:3811-73-2.mol
  • 吡啶硫酮钠:吡啶硫酮钠(NPT)是目前效果最强的水溶性工业防霉防腐剂,具有高效、广谱、低毒、稳定的特点,可用于金属切削液、防锈液、乳胶漆、胶粘剂、皮革制品、纺织制品、铜板纸等领域。 EEC和GB7916—87规定化妆品中吡啶硫酮钠最大允许浓度质量分数为0.5%,仅用于用后洗掉的产品中。一般使用浓度250~1000mg/kg。也用于工业金属切削油作为防腐剂。
  • color:very deep brown
  • TCI Shanghai:2-巯基吡啶-N-氧化钠盐(40%的水溶液,约3.3mol/L) 2-Mercaptopyridine N-Oxide Sodium Salt (40% in Water, ca. 3.3mol/L)(3811-73-2)
  • 图谱信息:吡硫钠(3811-73-2)红外图谱(IR1)
  • 检测方法:T,NMR
  • Acros Organics:2-Mercaptopyridine-N-oxide,sodiumsalt,40w/w%aqueoussolution(3811-73-2)
  • MSDS 信息:2-Pyridinethiol-1-oxide sodium salt(3811-73-2).msds
  • 毒性:急性经口毒性:LD50(鼠)875mg/kg,LD50(小鼠)1172mg/kg。 亚慢性毒性(鼠): 经口服药75mg/kg·d,腹腔用药40mg/kg·d,30天后,未见有病理上的变化。 兔的眼睛刺激试验:质量分数为10%溶液pH7.8~7.9,无刺激作用。
  • Sigma Aldrich:3811-73-2(sigmaaldrich)
  • 敏感性:Hygroscopic
  • 用途一:化学抗菌剂,具有高效、广谱、低毒、水溶液稳定等特点
  • Alfa Aesar:2-巯基吡啶N-氧化物钠盐无水,98% 2-Mercaptopyridine N-oxide sodium salt anhydrous, 98%(3811-73-2)
  • 产品描述:吡硫钠又称吡啶硫酮钠、奥麦丁钠、吡硫霉净、α-巯基吡啶-N-氧化物钠,属于吡啶衍生物类杀菌剂,外观为黄色全浅粽色透明液体,熔点250℃,稍有特征气味。易溶于水和乙醇等有机溶剂,溶解度(以质量分数计):水53%,乙醇19%,聚乙二醇(PEG400)12%。最佳使用pH范围7~10,质量分数为2%水溶液pH值8.0。对光、氧化剂和强还原剂不稳定。非离子表面活性剂会使它有些微失活,它与重金属能发生螯合反应。主要应用领域包括:日化产品、胶粘剂、造纸、医药、农药、皮革制品、消毒用品等。
  • F:3-13

系列性分类