2-Amino-5-methylpyridine 2-氨基-5-甲基吡啶

CAS 1603-41-4 MFCD00006328

化学结构图

1603-41-4
SMILES: Cc1ccc(N)nc1

化学属性

Mol. FormulaC6H8N2
Mol. Weight108.14
Density1.068
Flash Point118°(244°F)
TSCAYes
Melting Point76-77°C
Boiling Point227°C at 760 mmHg
Appearance 本品为无色片状结晶，m.p.76.6℃，易溶于水，溶于甲苯、苯等有机溶剂。
Stability易吸潮

别名和识别编码

Chemical Name2-Amino-5-methylpyridine
CAS Number1603-41-4
Synonym 2-Amino-5-methylpyridine {LY} 2-Amino-5-methylpyridine {} {LY} 2-Amino-5-methylpyridine {} {} {LY} 2-Amino-5-methylpyridine {} {} {} {LY} 2-Amino-5-methylpyridine {} {} {} {} {LY} 2-Amino-5-methylpyridine {} {} {} {} {} {LY} 2-Amino-5-methylpyridine {} {} {} {} {} {} { {} {} {} {} {} {} {LY} 2-Amino-5-methylpyridine {} {} {} {} {} {} {} {LY} 2-Amino-5-methylpyridine {} {} {} {} {} {} {} {} {LY} 2-Amino-5-methylpyridine {} {} {} {} {} {} {} {} {} {LY} 2-Amino-5-methylpyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-5-methylpyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-5-methylpyridine {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-5-methylpyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-5-methylpyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Amino-5-methylpyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
MDL NumberMFCD00006328
EC Number216-503-5
Beilstein Registry Number107050
PubChem Substance ID87562278
Alfabeta NameMETHYLPYRIDINAMINE 52---
Reaxys-RN107050
Chemical Name Translation2-氨基-5-甲基吡啶
LabNetwork Molecule IDLN00181494
InChIInChI=1S/C6H8N2/c1-5-2-3-6(7)8-4-5/h2-4H,1H3,(H2,7,8)
Canonical SMILESNC(C=C1)=NC=C1C
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Building Blocks, C6, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines
  • Heterocycles
  • Amines
  • {uni_hamburg} no charge; nitrogen heterocycle; aromatic; 6RingOnly; 6ring; 1fragment
  • Aromatics
  • {Chemicalbook} 农药中间体: 杀虫剂中间体: 其他杀虫剂

相关文献及参考

  • Francotte, P., et al.: Bioorg. Med. Chem., 16, 9948 (2008),
  • Short: III/20a
  • Beilstein: 22,V,9,289
  • Short: EINECS
  • Sundaraganesan, N., et al.: J. Mol. Struc., 891, 284 (2008),

安全信息

Signal word Danger Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
Risk Statements
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
  • R25 Toxic if swallowed 吞咽有毒
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R24/25 Toxic in contact with skin and if swallowed 皮肤接触及吞食都有毒
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P301+P310+P330
  • P302+P350
  • P302+P352+P312+P361+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P332+P313
  • P337+P313
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSTJ5141000
Packing GroupIII
UN Number 2811 UN 2811 6.1/PG 2 UN2811
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {}
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H301+H311
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H331 Toxic if inhaled 吸入中毒
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes T T,Xi
Warnings IRRITANT
Hazard Class6.1 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AJEBAK Australian Journal of Experimental Biology and Medical Science.
   (Adelaide, S.A., Australia) V.1-64, 1924-86.  Volume(issue)/page/year:
   36,491,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,841,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,841,1986

其他信息

  • 2-氨基-5-甲基吡啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 A0732 6-氨基-3-甲基吡啶 2-Amino-5-methylpyridine 500G 4650元 2011/04/16 A0732 6-氨基-3-甲基吡啶 2-Amino-5-methylpyridine 25G 580元 2010/06/21 SB01317EA 2-氨基-5-甲基吡啶 5-methylpyridin-2-amine 10 GR 255元
  • 灭火剂:干粉、泡沫、砂土, 二氧化碳, 雾状水
  • Hazard Note:Irritant
  • 2-氨基-5-甲基吡啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 A0732 6-氨基-3-甲基吡啶 2-Amino-5-methylpyridine 500G 4860元 2014/06/02 A0732 6-氨基-3-甲基吡啶 2-Amino-5-methylpyridine 25G 604元 2010/06/21 SB01317EA 2-氨基-5-甲基吡啶 5-methylpyridin-2-amine 10 GR 255元
  • Acros Orga
  • 可燃性危险特性:可燃;燃烧产生有毒氮氧化物烟雾
  • 类别:有毒物品
  • 图谱信息:2-氨基-5-甲基吡啶(1603-41-4)核磁图( 13 CNMR) 2-氨基-5-甲基吡啶(1603-41-4)质谱(MS) 2-氨基-5-甲基吡啶(1603-41-4)红外图谱(IR1) 2-氨基-5-甲基吡啶(1603-41-4)红外图谱(IR2) 2-氨基-5-甲基吡啶(1603-41-4)核磁图( 1 HNMR)
  • Alfa Aesar:2-氨基-5-甲基吡啶,99% 2-Amino-5-methylpyridine, 99%(1603-41-4)
  • 用途一:2-氨基-5-甲基吡啶是杀虫剂吡虫啉、啶虫脒的中间体。
  • 敏感性:Hygroscopic
  • MOL 文件:1603-41-4.mol
  • 上游原料:氢溴酸 --> 三甲胺 --> 氯甲烷 --> 三甲胺盐酸盐 --> 3-甲基吡啶氧化物 --> 5-甲基吡啶
  • 储运特性:库房通风低温干燥
  • LD50 1175mg/kg/日, 易溶于水。
  • 检测方法:HPLC
  • 下游产品:2-氯-5-甲基吡啶 --> 6-氨基烟酸乙酯 --> 5-甲氧基甲基-吡啶-2-氨基甲酸叔丁酯 --> 5-甲基-3-氨基-2-氯吡啶 --> 6-氨基烟酸 --> 6-氨基-3-吡啶基甲醇 --> (5-羟甲基吡啶-2-基)氨基叔丁酯 --> 6-叔丁氧羰基氨基烟酸甲酯 --> 6-氨基烟酸甲酯 --> 萘啶酸 --> 2-氯-5-甲基-3-硝基吡啶 --> 6-氨基烟酰肼 --> 2-溴-3-硝基-5-甲基吡啶 --> 2,3-二氯-5-三氟甲基吡啶 --> 2-氨基-3-溴-5-甲基吡啶 --> 2-羟基-5-甲基-3-硝基吡啶 --> 6-乙酰氨基烟酸甲酯 --> 6-氟烟酸 --> 2-乙酰氨基-3-溴-5-甲基吡啶 --> 6-乙酰氨基烟酸 --> 5-甲基-2-氨基-3-硝基吡啶 --> 2-氟-5-甲基吡啶 --> 2-乙酰氨基-5-甲基吡啶
  • 方法一:其制备方法是在二氯甲烷中加入三甲胺和3-甲基吡啶-N-氧化物，冷却至5℃，加入氯化亚砜的二氯甲烷溶液，搅拌过液，蒸去溶剂，得到(5-甲基吡啶-2-基)三甲基氯化铵，然后再加入溴氢酸，在200～210℃进行裂解可得产品。
  • {Chemicalbo
  • 毒性分级:高毒
  • TCI S
  • Sigma Aldrich:1603-41-4(sigmaaldrich)
  • 急性毒性:口服-大鼠LD50: 200毫克/公斤; 皮下-小鼠LD50: 110 毫克/公斤
  • MOL 文件:2454-96-8.mol
  • 海关编码:29333999

系列性分类

  1. Chemical Synthesis 化学合成
  2. Catalysis and Inorganic Chemistry 催化剂和无机化学
  3. Niobium - Catalysis and Inorganic Chemistry
  1. C6 - Pyridines
  1. C6 to C7 - Pyridines
  1. C5
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Pyridines 吡啶

相关产品推荐

120-80-9
67-51-6
695-34-1
1824-81-3
462-08-8
7440-06-4
5153-40-2
1336-21-6
2156-56-1
462-08-8
7440-06-4