1,3-Benzenediamine dihydrochloride 间苯二胺盐酸盐

CAS 541-69-5 MFCD00012975

化学结构图

541-69-5
SMILES: Cl.Cl.Nc1cccc(N)c1

化学属性

Mol. FormulaC6H10Cl2N2
Mol. Weight181
Melting Pointca 260° dec.
TSCAYes
Solubility易溶
Density1.05
Appearance 白色或微带红色的结晶性粉末,在空气中变色,易溶于水,能溶于醇。有毒。
Stability对光线和空气敏感

别名和识别编码

Chemical Namebenzene-1,3-diamine dihydrochloride
MDL NumberMFCD00012975
CAS Number541-69-5
PubChem Substance ID10941
Beilstein Registry Number3911748
EC Number208-790-0
Merck Number7283
Synonym 1,3-BENZENEDIAMINE DIHYDROCHLORIDE 1,3-Benzenediamine hydrochloride 1,3-Diaminobenzene Dihydrochloride 1,3-PHENYLENEDIAMINE DIHYDROCHLORIDE 1,3-Phenylenediamine dihydrochloride 1,3-benzenediaminehydrochloride 1,3-苯二胺二盐酸盐 1,3-苯二胺二盐酸盐; 1,3-二氨基苯盐酸盐; 间二氨基苯盐酸盐;间苯二胺 二盐酸盐 1,4-benzenediamine 1,4-phenyldiamine 1,4-phenylenediamine 3-AMINOANILINE DIHYDROCHLORIDE 4-p 4-phenylenediamine 4-phenylenediamine bromide, ion(1+) 4-phenylenediamine dihydrochloride 4-phenylenediamine diperchlorate 4-phenylenediamine ion (1+) 4-phenylenediamine monohydrobromide 4-phenylenediamine monohydrochloride 4-phenylenediamine monohydroiodide 4-phenylenediamine monooxalate 4-phenylenediamine monoperchlorate 4-phenylenediamine monosulfate
Reaxys-RN3911748
Chemical Name Translation间苯二胺盐酸盐
Wiswesser Line NotationZR CZ &GH 2
LabNetwork Molecule IDLN00222895
InChIInChI=1S/C6H8N2.2ClH/c7-5-2-1-3-6(8)4-5;;/h1-4H,7-8H2;2*1H
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分类

  • {SNA} Amine Salts, Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks

产品应用

  • 用作分析试剂和染料中间体。

相关文献及参考

  • Merck:14,7283
  • Merck:14,7283 Beilstein:13,38

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P203
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P310
  • P301+P310+P330
  • P301+P316
  • P302+P350
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P307+P311
  • P308+P313
  • P308+P316
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医,如果你觉得不舒服
  • P316
  • P318
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P333+P313
  • P333+P317
  • P337+P313
  • P337+P317
  • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
  • P361+P364
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H301+H311+H331
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H331 Toxic if inhaled 吸入中毒
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
RTECSSS9800000
Signal word Danger
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
  • S1/2 None 上锁保管并避免儿童触及;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Packing GroupIII
UN Number 2811 UN 2811 6.1/PG 3
Risk Statements
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R36 Irritating to eyes 刺激眼睛
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
  • R50/53
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
Hazard Codes 6.1 T,N
Hazard Class6.1
Storage condition 充氩储存
Warnings 危化品目录(2015)
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1800 mg/kg/21W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   KJMSAH Kyushu Journal of Medical Science.  (Fukuoka, Japan)  V.6-15,
   1955-64.  Discontinued.  Volume(issue)/page/year: 13,175,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD414-344

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 325 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCIBR* Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the
   National Cancer Institute by Bio-Research Consultants, Inc. (9 Commercial
   Ave., Cambridge, MA 02141)  Volume(issue)/page/year: NCI-E-68-1311,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KJMSAH Kyushu Journal of Medical Science.  (Fukuoka, Japan)  V.6-15,
   1955-64.  Discontinued.  Volume(issue)/page/year: 13,175,1962

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 50 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 7,535,1985

Restrict 危险品

其他信息

  • 急性毒性:腹腔-大鼠 LD50: 325 毫克/公斤; 腹腔-小鼠 LD50: 100 毫克/公斤
  • 储运特性:库房通风低温干燥; 与食品原料分开储运
  • 毒性分级:高毒
  • 用途一:用作分析试剂和染料中间体
  • Acros Organics:甲基丙烯醇-3-三甲氧基硅基丙酯(盐酸间苯二胺) m-Phenylenediamine dihydrochloride, 99%(541-69-5)
  • F:8-9-23
  • 图谱信息:1,3-苯二胺盐酸盐(541-69-5)红外图谱(IR2) 1,3-苯二胺盐酸盐(541-69-5)核磁图( 13 CNMR) 1,3-苯二胺盐酸盐(541-69-5)红外图谱(IR1)
  • 下游产品:1,3-二碘苯
  • 用途二:用作分析试剂和染料中间体。
  • 灭火剂:雾状水、二氧化碳、砂土、泡沫
  • MOL 文件:541-69-5.mol
  • 在空气中变色,易溶于水,能溶于醇。有毒。
  • MSDS 信息:Benzene-1,3-diamine dihydrochloride(541-69-5).msds
  • TCI Shanghai:1,3-苯二胺二盐酸盐 1,3-Phenylenediamine Dihydrochloride,>;99.0%(T)(541-69-5)
  • Sigma Aldrich:541-69-5(sigmaaldrich)
  • 可燃性危险特性:明火可燃; 受热放出有毒氯化氢和氧化氮气体
  • 1,3-苯二胺盐酸盐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80100214 间苯二胺盐酸盐 25g 12元 2011/04/16 P0172 1,3-苯二胺二盐酸盐 1,3-Phenylenediamine Dihydrochloride 500G 2760元 2011/04/16 P0172 1,3-苯二胺二盐酸盐 1,3-Phenylenediamine Dihydrochloride 25G 320元
  • Alfa Aesar:间苯二胺二盐酸盐,98% m-Phenylenediamine dihydrochloride, 98%(541-69-5)
  • 类别:有毒物品

系列性分类