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• 试剂商城
• 直接询价

分类

• {SNA} Chromatography Reagents & Solvents, HybridSPE-Phospholipid Technology, LC-MS Mobile Phase Additives, LC-MS Solvents & Reagents (CHROMASOLV), Precipitation Solvents, Blends, Additives, Sample Preparation & Purification, Solid Phase Extraction (SPE), 分析/色谱, 分析试剂
• {S
• {SNA} Analytical Standards,
• {SNA} Chromatography Reagents & Solvents, UHPLC-MS Mobile Phase Additives, UHPLC-MS and UHPLC-UV Solvents, Additives and Blends (Application tested), 分析/色谱, 分析试剂
• {SNA} Acids, Acids & Bases, Analytical Reagents, Analytical/Chromatography, Buffers & Reagents, Chemical Synthesis, Chromatography Reagents & Solvents, HPLC, HPLC Buffers,
• {SNA}
• {SNA} Acids, Acids & Bases,

产品应用

• 还原剂，测定砷、铋、铝、铜、金、铟、铁、铅、锰、汞、钼、银和锌等，检定铈，铼和钨，检验芳香族伯胺和仲胺，测定分子量及结晶的溶剂，测定甲氧基，显微分析中用作固定剂，制造甲酸盐类。

相关文献及参考

• In the presence of Raney nickel alloy, reduces aromatic nitriles to aldehydes in high yield: J. Chem. Soc., 5775 (1965); for list of examples, see: Org. Synth. Coll., 6, 631 (1988).
• Merck: 14,4241 Beilstein:2(4)3
• Merck: 14,4241
• Dehydration with sulfuric acid can be used to generate CO in situ. Subsequent reaction with tertiary carbocations gives the corresponding carboxylic acid (the Koch-Haaf carboxylation). For examples, see: Org. Synth. Coll., 5, 20, 739 (1973); improved procedure: Synth. Commun., 19, 1945 (1989). 1,4-Diols in which one alcohol is tertiary give -lactones: Che
• Used in combination with formaldehyde in the Eschweiler-Clarke reductive methylation of amines, the formic acid acting as a hydride donor. Review: Org. React., 5, 290 (1949). For an example, see: Org. Synth. Coll., 3, 723 (1955).
• In combination with Selenium(IV)­ oxide, 12358, improved results have been obtained in the allylic oxidation of sterically-hindered olefins: Synth. Commun., 24, 29213 (1994).
• Instead of the unstable formic anhydride, formylations may be carried out with formic acid and acetic anhydride to generate the mixed acetic formic anhydride in situ. For a review, see: Tetrahedron, 46, 1081 (1990). This reagent has been used for the deoxygenation of tertiary amine oxides: Chem. Lett., 1517 (1985).
• Cleaves trityl groups selectively in the presence of benzylidene acetals or TBDMS ethers: T
• Hydrogen donor, in combination with Pd on carbon, in catalytic transfer hydrogenations; see, e.g.: Selective reduction of dinitroarenes to nitroanilines: J. Org. Chem., 45, 4992 (1980). Dehalogenation of aryl halides: Synthesis, 876 (1982). Hydrogenation of aromatic rings: Tetrahedron Lett., 33, 7477 (1992). See also Palladium, A12012, Cyclohexene, A11359, and Ammonium formate, A10699. For a comparative mechanistic study of formic acid and formate salts in hydrogenolysis of aryl chlorides, see: J. Org. Chem., 60, 1347 (1995).

安全信息

GHS Symbol

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 15 gm/m3/15M
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co.,
   1956-59  Volume(issue)/page/year: 1,146,1955

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 15 gm/m3/15M
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 23(12),49,1979

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 239 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Sa

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF E

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Non-mammalian species Cells - not otherwise specified
DOSE/DURATION           : 100 mmol/L
REFERENCE :
   CAANAT Comptes Rendus de l'Association des Anatomistes.  (Nancy, France)
   V.1-56, 1899-1972.  For publisher information, see ANOBAU.
   Volume(issue)/page/year: 56,712,1972

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 240,195,1990

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Inhalati

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 70 ppm/3H
REFERENCE :
   AMNTA4 American Naturalist.  (Univ. of Chicago Press, Journals Div., POB
   37005, Chicago, IL 60637) V.1-    1867-  Volume(issue)/page/year:
   85,119,1951

TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 100 mmol/L
REFERENCE :
   MDMIAZ Medycyna Doswiadczalna i Mikrobiologia.  For English translation, see
   EXMMAV.  (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland)  V.1-    1949-
   Volume(issue)/page/year: 31,11,1979

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Non-mammalian species Cells - not otherwise specified
DOSE/DURATION           : 100 mmol/L
REFERENCE :
   CAANAT Comptes Rendus de l'Association des Anatomistes.  (Nancy, France)
   V.1-56, 1899-1972.  For publisher information, see ANOBAU.
   Volume(issue)/page/year: 56,712,19

其他信息

• 能与水、醇、醚和甘油任意混合，对皮肤有腐蚀性。
• 具有刺激性气味，能与水、醇、醚、丙三醇相混合.