FAK

下级目录

PND-1186

Y11

9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one

GSK-2256098

SKLB1002

CEP-37440

LB42708

TAE226

Masitinib

Zibotentan (ZD4054)

PF-573228

目录项下的产品

1061353-68-1 / MFCD161353681
2-((2-((2-Methoxy-4-Morpholinophenyl)Amino)-5-(Trifluoromethyl)Pyridin-4-Yl)Amino)-N-Methylbenzamide
2-((2-((2-甲氧基-4-吗啉苯基)氨基)-5-(三氟甲基)吡啶-4-基)氨基)-N-甲基苯甲酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

1086639-59-9 / MFCD186639599
Y11

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

1124329-14-1 / MFCD224329141
AZ3146 is a novel and potent Mps1 inhibitor, which was used to probe the role of Mps1's catalytic activity during mitosis. AZ3146 also inhibits FAK, JNK1, JNK2, KSP and Kit. In in vitro kinase assays, AZ3146 inhibited human Mps1Cat with an IC50 (50% inhibitory concentration) of ~35 nM. AZ3146 also efficiently inhibited autophosphorylation of full-length Mps1 immunoprecipitated from human cells.
9-环戊基-2-[[2-甲氧基-4-[(1-甲基哌啶-4-基)氧基]-苯基]氨基]-7-甲基-7,9-二氢-8H-嘌呤-8-酮

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

1224887-10-8 / MFCD324887108
2-((5-Chloro-2-((1-Isopropyl-3-Methyl-1H-Pyrazol-5-Yl)Amino)Pyridin-4-Yl)Amino)-N-Methoxybenzamide
2-((5-氯-2-((1-异丙基-3-甲基-1H-吡唑-5-基)氨基)吡啶-4-基)氨基)-N-甲氧基苯甲酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

1225451-84-2 / MFCD325451842
SKLB1002
2-((6,7-二甲氧基喹唑啉-4-基)硫基)-5-甲基-1,3,4-噻二唑

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国

1391712-60-9 / MFCD491712609
CEP-37440
(S)-2-((5-氯-2-((6-(4-(2-羟乙基)哌嗪-1-基)-1-甲氧基-6,7,8,9-四氢-5H-苯并[7]轮烯-2-基)氨基)嘧啶-4-基)氨基)-N-甲基苯甲酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

226929-39-1 / MFCD26929391
LB42708

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

761437-28-9 / MFCD61437289
2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methylbenzamide
2-[[5-氯-2-[[2-甲氧基-4-(4-吗啉)苯基]氨基]-4-嘧啶]氨基]-N-甲基苯甲酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

广州市
中华人民共和国

790299-79-5 / MFCD09954132
Masitinib, also known as AB1010, is an orally bioavailable and multi-targeted protein tyrosine kinase inhibitor with potential antineoplastic activity. Masitinib selectively binds to and inhibits both the wild-type and mutated forms of the stem cell factor receptor (c-Kit; SCFR); platelet-derived growth factor receptor (PDGFR); fibroblast growth factor receptor 3 (FGFR3); and, to a lesser extent, focal adhesion kinase (FAK). As a consequence, tumor cell proliferation may be inhibited in cancer cell types that overexpress these receptor tyrosine kinases (RTKs). Masitinib was approved for veterinary use.
马塞替尼

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国

186497-07-4 / MFCD09955343
N-(3-Methoxy-5-Methylpyrazin-2-Yl)-2-(4-[1,3,4-Oxadiazol-2-Yl]Phenyl)Pyridine-3-Sulfonamide
N-(3-甲氧基-5-甲基吡嗪-2-基)-2-(4-[1,3,4-恶二唑-2-基]苯基)吡啶-3-磺酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

869288-64-2 / MFCD11519967
6-((4-((3-(Methylsulfonyl)Benzyl)Amino)-5-(Trifluoromethyl)Pyrimidin-2-Yl)Amino)-3,4-Dihydroquinolin-2(1H)-One
6-((4-((3-(甲磺酰基)苄基)氨基)-5-(三氟甲基)嘧啶-2-基)氨基)-3,4-二氢喹啉-2(1H)-酮

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

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