Dimethylamine 二甲胺

CAS 124-40-3 MFCD00008288

化学结构图

124-40-3
SMILES: CNC

化学属性

Mol. Formula(CH3)2NH
Mol. Weight45.08
Refractive index1.3700
Autoignition Point753 °F
Vapor Density1.55 (15 °C, vs air)
Vapor Pressure1277 mmHg ( 20 °C)
Density0.85
Boiling Point7 °C(lit.)
Melting Point-93 °C(lit.)
Flash Point15°(60°F)
TSCAYes
Solubility易溶于水,溶于乙醇、乙醚。
pH:A

别名和识别编码

Chemical NameDimethylamine
Synonym (CH3)2NH DIMETHYLAMINE DMA DMA-40 DMA-60 DMA-65 Dimethyl-amine Dimethylamin Dimethylamin ....% Dimethylamin, dimethylamine, aqueoussolution Dimethylamin-hydrat Dimethylamine Dimethylamine (anhydrous) Dimethylamine, Anhydrous LABOTEST-BB LTBB000394 Methanamine, N-methyl- N,N-Dimethylamine N-Methylmethanamin N-Methylmethanamine N-methylmethanamine N-甲基甲胺 N-甲基甲胺溶液 RCRA waste number U092 ai3-15638-x dimethylamine dimethylamine ....% dimethylamine hydrochloride dimethylamine monosulfate dimethylamine nitrate dimethylamine perchlorate dimethylamine phosphate (3:1)
Beilstein Registry Number605257
PubChem Substance ID674
MDL NumberMFCD00008288
EC Number204-697-4
CAS Number124-40-3
Merck Number14,3228
Chemical Name Translation二甲胺
Wiswesser Line Notation1M1
InChIInChI=1S/C2H7N/c1-3-2/h3H,1-2H3
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分类

  • {SA} Alphabetic, Analytical Standards, Analytical/Chromatography, Chemical Synthesis, D, DID - DIN, Organic Bases, Synthetic Reagents
  • {uni_hamburg} no charge; 1fragment
  • {SNA} Chemical Synthesis, Organic Bases, Synthetic Reagents
  • {SNA} 25mL Sure/Seal Reagents, Acids & Bases, Amines, Bases, Building Blocks, C2 to C5, Chemical Synthesis, Nitrogen Compounds, Organic Bases, Organic Building Blocks, Organometallic Reagents, Synthetic Reagents
  • {SNA} Acids & Bases, Bases, Chemical Synthesis, Organic Bases,

产品应用

  • ⑴. 二甲胺在室温下是无色气体。高浓度的带有氨味,低浓度的有烂鱼味。易溶于水,溶于乙醇和乙醚。易燃烧。
  • ⑵. 有弱碱性,与无机酸生成易溶于水的盐类。其蒸气能与空气形成爆炸性混合物,爆炸极限2.8%-14.4%。闪点低,避免日光直射,远离火源。对铜、铜合金、铝、锡、锌等有腐蚀性。
  • ⑶. 化学性质具有仲胺的典型性质。
  • ① 水溶液呈碱性,与无机酸、有机酸、酸性芳香族硝基化合物生成具有一定熔点的盐。与重金属化合物形成络盐。
  • ② 与酰氯、酸酐等发生酰基化反应,生成N-取代酰胺。与脂肪族羧酸生成的盐,经脱水后也生成
  • 测定镁和锌。氢氧化锌、氢氧化锰的沉淀。酸性气体吸收剂。溶剂。检验氯化苦及空气中二氧化碳。有机合成中间体,二甲基二硫代氨基甲酸盐等制备。

相关文献及参考

  • Short: II/4
  • Merck: 14,3228
  • Short: II/6
  • Short: II/25B
  • Merck: 14,3228 Beilstein: 4,IV,128

安全信息

GHS Symbol
WGK Germany2
Hazard statements
  • H220 Extremely flammable gas 极易燃气体。
  • H224 Extremely flammable liquid and vapour 极端易燃液体和蒸气
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H280 Contains gas under pressure; may explode if heated 内含高压气体,遇热可能爆炸。
  • H302 Harmful if swallowed 吞食有害
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H332 Harmful if inhaled 吸入有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter Eyeshields, Faceshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US) Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P242 Use only non-sparking tools. 只能使用无火花工具。
  • P243 Take precautionary measures against static discharge. 采取预防措施,防止静电放电。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P301+P312
  • P301+P330+P331
  • P302+P352
  • P303+P361+P353
  • P304+P312
  • P304+P340
  • P305+P351+P338
  • P307+P311
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医,如果你觉得不舒服
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P333+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P370+P378
  • P377 Leaking gas fire: Do not extinguish, unless leak can be stopped safely. 漏气着火:切勿灭火,除非漏气能够被安全地制止。
  • P381 Eliminate all ignition sources if safe to do so. 如果安全的话,消除所有点火源。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403 Store in a well-ventilated place. 储存在通风良好的地方。
  • P403+P233
  • P403+P235
  • P405 Store locked up. 上锁保管。
  • P410+P403
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word
RTECSIP8750000
Packing GroupII
UN Number UN2924 1160 UN1160
Risk Statements
  • R12 Extremely flammable 极端易燃
  • R11 Highly flammable 非常易燃
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R34 Causes burns 会导致灼伤
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
  • R20 Harmful by inhalation 吸入有害
  • R19 May form explosive peroxides 可能生成易爆的过氧化物质
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
Safety Statements
  • S29 Do not empty into drains 不要排入下水道;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Storage condition 密封保存 Flammables area Hygroscopic
Hazard Codes F,T F,C 3
Hazard Class3
Warnings 危化品目录(2015)
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4725 ppm/2H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   43,411,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 240 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - muscle weakness
   Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
   HYSAAV Hygiene and Sanitation (USSR).  English translation of GISAAA.
   (Springfield, VA)  1964-71. Discontinued.  Volume(issue)/page/year:
   32(6),329,1967

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4540 ppm/6H
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - effect, not otherwise
   specified
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 4

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 736 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 97,1117,1977

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 500 umol/L
REFERENCE :
   MOTOEX Molecular Toxicology. (Taylor & Francis, Inc., 242 Cherry St.,
   Philadelphia, PA USA 19106) V.1-   1987-  Volume(issue)/page/year:
   1,217,1987

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Inhalation
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 50 ug/m3
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 36(11),9,1971

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   MOTOEX Molecular Toxicology. (Taylor & Francis, Inc., 242 Cherry St.,
   Philadelphia, PA USA 19106) V.1-   1987-  Volume(issue)/page/year:
   1,217,1987

Restrict 危险品

其他信息

  • ⑴. 储存于阴凉、通风的库房。远离火种、热源。库温不宜超过30℃。保持容器密封。应与氧化剂、酸类、卤素单质分开存放,切忌混储。采用防爆型照明、通风设施。禁止使用易产生火花的机械设备和工具。储区应备有泄漏应急处理设备。 ⑵. 密闭操作,加强通风。操作人员必须经过专门培训,严格遵守操作规程。建议操作人员佩戴自吸过滤式防毒面具(全面罩),穿防静电工作服,戴橡胶手套。远离火种、热源,工作场所严禁吸烟。使用防爆型的通风系统和设备。防止气体泄漏到工作场所空气中。 ⑶. 在传送过程中,钢瓶和容器必须接地和跨接,防止产

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