Methylamine 甲胺

CAS 74-89-5 MFCD00008104

化学结构图

74-89-5
SMILES: CN

化学属性

Mol. FormulaCH3NH2
Mol. Weight31.06
Density0.785 g/mL at 25 °C
Autoignition Point806 °F
Vapor Density1.08 (20 °C, vs air)
Boiling Point40 °C
Vapor Pressure10.86 psi ( 55 °C)
Melting Point-93.5°C
Refractive indexn20/D 1.360-1.372
Flash Point-14°(6°F)
TSCAYes
Solubility易溶于水,溶于乙醇、乙醚等。
Stability对光和热敏感
pH-:A
Danger-Level-
Redox-

别名和识别编码

Chemical NameMethylamine
Synonym AKOS BBS-00004243 AMINE C1 AMINOMETHANE Aminomethan Aminomethane CH3NH2 Carbinamine MERCURIALIN METHYLAMINE METHYLAMINE METHANOL MMA MMA-40 MMA-50 MONOMETHYLAMINE Mercurialin Methanamine Methylamin Methylamine Methylaminen Metilamine Metyloamina Monomethylamin ....% Monomethylamine N-methylamine ai3-15637-x aminomethane anhydrousmethylamine methanamine methylamine methylamine (mono) methylamine bisulfite methylamine h methylamine hydride methylamine hydrobromide methylamine hydrochloride
MDL NumberMFCD00008104
CAS Number74-89-5
Beilstein Registry Number741851
EC Number200-820-0
PubChem Substance ID6329
Merck Number14,6014
Chemical Name Translation甲胺
Wiswesser Line NotationZ1
InChIInChI=1S/CH5N/c1-2/h2H2,1H3
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分类

  • {SNA} Acids & Bases, Alternative Energy,
  • {SNA} Acids & Bases,
  • {SNA} Acids & Bases, Alternative Energy, Bases, Chemical Synthesis, Materials Science, Methylamine Products, Organic Bases, Perovskite Materials, Synthetic Reagents
  • {uni_hamburg} no charge; 1fragment
  • {SNA} 12 Principles Aligned Products,
  • {SNA} Acids & Bases, Alternative Energy, Bases, Chemical Reagents, Chemical Synthesis, Development Quantities for Research, Enabling Products, Greener Alternative Products, Material Sciences, Organic Bases, Organohalide Products, Perovskite Materials, Synthetic Reagents, 材料科学
  • {SNA} Acids & Bases,

产品应用

  • 分解产物为氨,属低毒类,具有刺激性和腐蚀性。
  • 氨中的一个氢被甲基取代后所形成的衍生物。甲胺是最简单的伯胺。
  • ⑴、甲胺水溶液或醇溶液均为易燃液体。由于闪点低,易挥发,有毒,和空气会形成爆炸性混合物,避免日光照射和使用易发生静电的装置。甲胺对铜或铜合金、铝、锡和镀锌铁板有腐蚀性。易燃。
  • ⑵、化学性质具有伯胺的典型反应:
  • ① 水溶液呈碱性,与无机酸、有机酸、酸性芳香族硝基化合物等作用生成具有一定熔点的盐。与铜、银等重金属氯化物生成络盐。
  • ② 与酰氯、酸酐等发生酰基化反应,生成N-取代酰胺。与羧酸生成的盐再经脱水
  • 有机合成。有机溶剂。

相关文献及参考

  • Short: II/14a Title: Molecular Constants: Diamagnetic Molecules Author: Demaison, J.; Dubrulle, A.; Hüttner, W.; Tiemann, E. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: II/14a Page: 1-788 Year: 1982 Keyword: organic compounds; molecular constants; spectroscopy; microwave spectroscopy ISBN: 3-540-11365-7 ISBN: 978-3-540-11365-2 Internet Resource: DOI:10.1007/b19966 RefComment: 196 figs., XI
  • Short: II/19b Title: Molecular Constants: Rotational, Centrifugal Distortion and Related Constants of Diamagnetic Asymmetric Top Molecules Author: Demaison, J.; Hüttner, W.; Vogt, J.; Wlodarczak, G. Editor: Hüttner, W. Source: Landolt-Börnstein, New Series Volume: II/19b Year: 1992 Keyword: organic compounds; molecular constants; spectroscopy; microwave spectroscopy ISBN: 3-540-54578-6 ISBN: 978-3-540-54578-1 Internet Resource: DOI:10.1007/b44334 RefComment: XI, 488 pages. Abstract: Volume II/19 Molecular Constants mostly from Microwave, Molecular Beam and Sub-Doppler Laser Spectroscopy is a supplement to the earlier volumes II/4, II/6, and II/14. The slight change in the title reflects current trends in the applications of spectroscopic methods. Together, the four volumes collect all the critically evaluated data published up to 1989/90 on constants of free molecules obtained by classical and modern spectroscopy. Volume II/19 is divided into four parts to record the growing number of investigations, especially in the microwave and millimeter wave regions, where modern techniques like Fourier Transform Microwave Spectroscopy have made new objects of interest such as molecular complexes and clusters accessible to study. Subvolume II/19b contains corresponding data on diamagnetic asymmetric top molecules.
  • Short: II/19c Title: Molecular Constants: Dipole Moments, Quadrupole Coupling Constants, Hindered Rotation and Magnetic Constants of Diamagnetic Molecules Author: Demaison, J.; Hüttner, W.; Tiem

安全信息

GHS Symbol
WGK Germany2
Hazard statements
  • H220 Extremely flammable gas 极易燃气体。
  • H224 Extremely flammable liquid and vapour 极端易燃液体和蒸气
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H280 Contains gas under pressure; may explode if heated 内含高压气体,遇热可能爆炸。
  • H301 Toxic if swallowed 吞食有毒
  • H302 Harmful if swallowed 吞食有害
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H331 Toxic if inhaled 吸入中毒
  • H332 Harmful if inhaled 吸入有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H351 Suspected of causing cancer 怀疑致癌
  • H370 Causes damage to organs 导致器官损伤
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSPF6300000
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P203
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P222 Do not allow contact with air. 不要与空气接触。
  • P230 Keep wetted with … 保持湿润
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P242 Use only non-sparking tools. 只能使用无火花工具。
  • P243 Take precautionary measures against static discharge. 采取预防措施,防止静电放电。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P310
  • P301+P312
  • P301+P316
  • P301+P317
  • P301+P330+P331
  • P302+P352
  • P302+P361+P354
  • P303+P361+P353
  • P304+P312
  • P304+P340
  • P304+P340+P310
  • P305+P351+P338
  • P305+P354+P338
  • P307+P311
  • P308+P313
  • P308+P316
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医,如果你觉得不舒服
  • P316
  • P317
  • P318
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P370+P378
  • P377 Leaking gas fire: Do not extinguish, unless leak can be stopped safely. 漏气着火:切勿灭火,除非漏气能够被安全地制止。
  • P381 Eliminate all ignition sources if safe to do so. 如果安全的话,消除所有点火源。
  • P403 Store in a well-ventilated place. 储存在通风良好的地方。
  • P403+
Signal word Danger
Safety Statements
  • S29 Do not empty into drains 不要排入下水道;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S3/7 Keep container tightly closed in a cool place 将容器严格密闭保存在阴凉处;
  • S39 Wear eye/face protection 戴眼睛/面孔保护装置;
  • S3 Keep in a cool place 保存在阴凉处;
  • S7 Keep container tightly closed 保存在严格密闭容器中;
  • S33 Take precautionary measures against static discharges 对静电采取预防措施;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Packing GroupII
UN Number UN2924 1235 UN1235 UN 3286 3/PG 2
Risk Statements
  • R12 Extremely flammable 极端易燃
  • R20 Harmful by inhalation 吸入有害
  • R19 May form explosive peroxides 可能生成易爆的过氧化物质
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R11 Highly flammable 非常易燃
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
  • R37 Irritating to respiratory system 刺激呼吸道
  • R34 Causes burns 会导致灼伤
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
Hazard Codes Xn;F+ 3 F+,Xn,C,F,T F,T F,C F,Xn
Hazard Class3
Storage condition 安瓿或气瓶盛装阴凉保存。 Flammables area 2-8℃ 2-8℃ 安瓿或气瓶盛装阴凉保存。充氩保存
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2400 mg/m3/2H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,81,1982

TYPE OF TEST            : LD5

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem.

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 2400 mg/m3
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv.
   Toxicology of New Industrial Chemical Substances.  For English translation,

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 3 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 174,285,1986

TYPE OF TEST            : Dominant lethal test
ROUTE OF EXPOSURE       : Inhalation
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 10 ug/m3
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 46(5),7,1981

Restrict 易制爆

其他信息

  • ⑴. 储存于阴凉、通风的库房。采用防爆型照明、通风设施。远离火种、热源。库温不宜超过30℃。 ⑵. 保持容器密封。应与氧化剂、酸类、卤素、氯仿等分开存放,切忌混储。 ⑶. 禁止使用易产生火花的机械设备和工具。储区应备有泄漏应急处理设备。

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