c-Kit

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Henatinib

Chiauranib

瓦他拉尼碱二盐酸盐

3-[2,4-dimethyl-5-[(E)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid

PD-173955

AAL-993

Crenolanib

OSI-930

N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide

AZD-2932

Ganetespib

TYRPHOSTIN AG 490

SU54161

Masitinib

Tandutinib

1-(2,4-Difluorophenyl)-3-(4-(6,7-dimethoxyquinolin-4-yloxy)-2-fluorophenyl)urea

5-[4-[(2,3-Dimethyl-2H-indazol-6-yl)-methyl-amino]-pyrimidin-2-ylamino]-2-methyl-benzenesulfonamide

目录项下的产品

1239269-51-2 / MFCD339269512
Henatinib maleate is t he maleate salt form of henatinib, an orally bioavalable, multitargeted tyrosine kinase inhibitor with potential antitumor and antiangiogenic activities. Henatinib inhibits vascular endothelial growth factor receptor type 2 (VEGFR2), a tyrosine kinase receptor upregulated in many tumor cells that plays a key role in angiogenesis. This may result in an inhibition of angiogenesis and eventually tumor cell proliferation. Henatinib, structurally similar to sunitinib, also inhibits, though to a lesser extent, mast/stem cell growth factor receptor (c-Kit) and, platelet-derived growth factor receptor (PDGFR) alpha and beta. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

1256349-48-0 / MFCD356349480
N-(2-Aminophenyl)-6-[(7-methoxy-4-quinolinyl)oxy]-1-naphthalenecarboxamide
N-(2-氨基苯基)-6-[(7-甲氧基-4-喹啉基)氧基]-1-萘甲酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国

212141-51-0 / MFCD12141510
Vatalanib Dihydrochloride
瓦他拉尼二盐酸盐

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国

252916-29-3 / MFCD52916293
3-[2,4-dimethyl-5-[(E)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

260415-63-2 / MFCD60415632
6-(2,6-Dichlorophenyl)-8-methyl-2-((3-(methylthio)phenyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
6-(2,6-二氯苯基)-8-甲基-2-((3-(甲硫基)苯基)氨基)吡啶并[2,3-d]嘧啶-7(8H)-酮

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

269390-77-4 / MFCD69390774
AAL-993 is a highly potent inhibitor of VEGFR-1 (IC50 =130nM), VEGFR-2 (IC50=23nM) and VEGFR-3 (IC50=18nM). At higher concentrations it inhibits PDGFR-β (640nM), c-Kit (236nM) and CSF-1R (380nM).

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

670220-88-9 / MFCD70220889
1-[2-[5-[(3-Methyl-3-Oxetanyl)Methoxy]-1-Benzimidazolyl]-8-Quinolyl]-4-Piperidinamine
[1-[2-[5-(3-甲基氧杂环丁烷-3-基甲氧基)苯并咪唑-1-基]喹啉-8-基]哌啶-4-基]胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

728033-96-3 / MFCD28033963
3-((Quinolin-4-Ylmethyl)Amino)-N-(4-(Trifluoromethoxy)Phenyl)Thiophene-2-Carboxamide
3-((喹啉-4-基甲基)氨基)-N-(4-(三氟甲氧基)苯基)噻吩-2-甲酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

850879-09-3 / MFCD50879093
N-(Benzo[D][1,3]Dioxol-5-Ylmethyl)-4-(Benzofuro[3,2-d]Pyrimidin-4-Yl)Piperazine-1-Carbothioamide
N-(苯并[d][1,3]二氧杂环戊烷-5-基甲基)-4-(苯并呋喃并[3,2-d]嘧啶-4-基)哌嗪-1-甲硫酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

883986-34-3 / MFCD83986343
2-(4-((6,7-Dimethoxyquinazolin-4-yl)oxy)phenyl)-N-(1-isopropyl-1H-pyrazol-4-yl)acetamide
2-(4-((6,7-二甲氧基喹唑啉-4-基)氧基)苯基)-N-(1-异丙基-1H-吡唑-4-基)乙酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

888216-25-9 / MFCD88216259
Ganetespib
Ganetespib

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国

133550-30-8 / MFCD00209833
(E)-N-Benzyl-2-Cyano-3-(3,4-Dihydroxyphenyl)Acrylamide
(E)-N-苄基-2-氰基-3-(3,4-二羟苯基)丙烯酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

204005-46-9 / MFCD01940922
3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
1,3-二氢-3-[(3,5-二甲基-1H-吡咯-2-基)亚甲基]-2H-吲哚-2-酮

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国
√

790299-79-5 / MFCD09954132
Masitinib, also known as AB1010, is an orally bioavailable and multi-targeted protein tyrosine kinase inhibitor with potential antineoplastic activity. Masitinib selectively binds to and inhibits both the wild-type and mutated forms of the stem cell factor receptor (c-Kit; SCFR); platelet-derived growth factor receptor (PDGFR); fibroblast growth factor receptor 3 (FGFR3); and, to a lesser extent, focal adhesion kinase (FAK). As a consequence, tumor cell proliferation may be inhibited in cancer cell types that overexpress these receptor tyrosine kinases (RTKs). Masitinib was approved for veterinary use.
马塞替尼

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国

387867-13-2 / MFCD09954147
N-(4-Isopropoxyphenyl)-4-(6-Methoxy-7-(3-(Piperidin-1-Yl)Propoxy)Quinazolin-4-Yl)Piperazine-1-Carboxamide
N-(4-异丙氧基苯基)-4-(6-甲氧基-7-(3-(哌啶-1-基)丙氧基)喹唑啉-4-基)哌嗪-1-甲酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

228559-41-9 / MFCD09971092
1-(2,4-difluorophenyl)-3-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-2-fluorophenyl)urea
1-(2,4-二氟苯基)-3-(4-((6,7-二甲氧基喹啉-4-基)氧基)-2-氟苯基)脲

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国
√

444731-52-6 / MFCD11616589
Pazopanib
帕唑帕尼

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国
√

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