• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Alternative Energy, Aluminum Hydrides, Chemical Synthesis,
• {SNA} Aluminum Hydrides, Chemical Synthesis, Reduction, Synthetic Reagents
• {SNA} Alternative E
• {SNA} 25mL Sure/Seal Reagents, Aluminum Hydrides,
• {SNA} Alternative Energy, Aluminum Hydrides, Chemical Synthesis, Materials Science, Materials for Hydrogen Storage, Metal Hydrides, Reduction, Synthetic Reagents
• {SNA} Alternative Energy, Aluminum Hydrides, Chemical Synthesis, Enabling Products, Greener Alternative Products,
• {SNA} 25mL Sure/Seal Reagents, Aluminum Hydrides, Chemical Synthesis, Organometallic Reagents, Reduction, Synthetic Reagents

产品应用

• ⑴.具有高度可燃性，必须隔绝空气、湿气，并最好在氮气氛下保存。
• ⑵. 羰基试剂。还原剂。制造其他氢化物及硅烷、硼烷等。在医药、香料、农药、染料及其他精细有机合成中用作还原剂。可将醛酮、酸、酸酐、酯、醌、酰氯等还原为醇，将腈还原为伯胺，将卤化烃还原为烃，芳香硝基化合物还原成偶氮化合物。但通常不能使碳—碳双键氢化。100份乙醚能溶本品30份，100份四氢呋喃能溶13份，100份二甲基溶纤剂能溶10份，100份二丁醚能溶2份，100份二氧六环能溶0.1份。
• ⑶. 是有机化学中一个常用的还原试剂，能够还原多种官能
• A powerful reagent and reducing agent.

相关文献及参考

• For reduction of sulfones, see Titanium(IV)­ chloride, 14713.
• For THF, at least 10ml solvent per gram of reagent is recommended to absorb heat of mixing.
• The use of water or steam baths, or of electric heating mantles is to be strongly discouraged.
• The reduction reaction should preferably be controlled by adjusting the rate of addition of the substrate rather than relying on external heating or cooling.
• Short: IV/19A1
• Many procedures for reactions with this reagent which have been described in the literature are potentially unsafe on anything other than a very small scale, since often no precautions are given for mixing the reagent with flammable solvents. The following suggestions are offered for laboratory scale reductions:
• Short: III/14a
• Merck: 14,349
• Efficient stirring is essential during mixing, reaction and workup.
• For phase-transfer reductions in hydrocarbon solvents, see 15-Crown-5, A12265. For formation of lithium tris(diethylamino)aluminum hydride and use in the reduction of esters or amides to aldehydes, see Diethyl­amine, A11716. For formation of a reagent for reduction of carboxylic acids to aldehydes, see 1-Methyl­piperazine, A10837.
• External heating or cooling, if required, should be by means of a suitable inert oil.
• Monograph: J. Seyden-Penne, Reductions by the Alumino- and Borohydrides In Organic Synthesis, 2nd ed., Wiley, N.Y. (1997).
• Mixing with a flammable solvent must always be carried out under an inert atmosphere.
• Reverse addition (solvent to reagent), if done rapidly, may be safer.
• The use of Diethoxymethane, B23134 as a reaction solvent has also been recommended.
• Short: III/35C4

安全信息

其他信息

• ⑴. 储存于阴凉、干燥、通风良好的专用库房内，远离火种、热源。库温不超过32℃，相对湿度不超过75%。包装密封。 ⑵. 应与氧化剂、酸类、醇类等分开存放，切忌混储。储区应备有合适的材料收容泄漏物。